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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
lysyl-tRNA synthetase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "lysyl-tRNA synthetase" in MCE Product Catalog:
1
1 Cited Publications
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LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.015 μM and 0.13 μM for Plasmodium falciparum lysyl-tRNA synthetase (PfKRS) and Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS), respectively .
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LysRs-IN-1 is a Lysyl-tRNA synthetase (LysRs) inhibitor.
Cat. No.: HY-15782
CAS No.: 1428623-14-6
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YH16899 binds Lysyl-tRNA synthetase (KRS), and inhibits membrane translocation of KRS. YH16899 impares the interaction of KRS with 67LR. YH16899 inhibits tumor metastasis in mouse models .
Cat. No.: HY-168569
CAS No.: 3003871-42-6
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DDD489 is a potent and selective Cryptosporidium lysyl-tRNA synthetase (CpKRS) inhibitor with IC50 values of 0.85 uM.DDD489 shows anti-cryptosporidials activity in vitro and in vivo .
Cat. No.: HY-175503
CAS No.: 2973324-63-7
LysRS-IN-4 (Compound 49) is an orally active Mycobacterium tuberculosis LysRS (lysyl-tRNA synthetase) inhibitor. LysRS-IN-4 is promising for research of tuberculosis .
Cat. No.: HY-175305
CAS No.: 3052352-22-1
DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research .
Cat. No.: HY-P70840
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KARS1; LysRS; Prev. KARS; KIAA0070; Prev. DFNB89; CMTRIB; lysyl-tRNA synthetase; DEAPLE; Lysine--tRNA Ligase; LEPID; KARS2; KRS; Lysine tRNA Ligase; lysyl-tRNA synthetase 1; Deafness, Autosomal Recessive 89
Species:
Human
Source:
HEK293
Cat. No.: HY-P991156
CAS No.: 2994192-38-8
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Cat. No.: HY-184406
Antimalarial agent 65 is an inhibitor of Plasmodium falciparum lysyl-tRNA synthetase (PfKRS1), with a pIC50 value of 6.9 against Plasmodium falciparum. Antimalarial agent 65 inhibits the growth of Plasmodium falciparum strains. Antimalarial agent 65 exhibits activity across multiple life cycle stages of the malaria parasite, including transmission-blocking activity. Antimalarial agent 65 can be used in malaria-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
