62 Results for "

manganese

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "manganese" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-B0885
CAS No.: 27220-47-9
Synonyms: (±)-Econazol
Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .
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2
2 Cited Publications
Cat. No.: HY-13336
CAS No.: 218791-21-0
Purity:  98.15%
Synonyms: M40403; GC4403
Target:  

SOD

Research Areas:  

Cancer

Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
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2
2 Cited Publications
Cat. No.: HY-W001583
CAS No.: 53177-12-1
Synonyms: EUK-8
Research Areas:  

Cardiovascular Disease

Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine .
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1 Cited Publications
Cat. No.: HY-109521A
CAS No.: 13446-34-9
Purity:  99.08%
Synonyms: manganese(Ⅱ) chloride tetrahydrate, molecular biology grade,≥99.0% (KT)
Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.
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1
1 Cited Publications
Cat. No.: HY-W019894
CAS No.: 7773-01-5
Synonyms: manganese dichloride
Manganese chloride is an orally active MRI liver contrast agent. Manganese chloride induces Apoptosis and activates the mTOR signaling pathway. Manganese chloride induces cognitive impairment, promotes hematopoietic recovery, and reduces radiation-induced bone marrow and brain damage. It can be used for the study of renal impairment .
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1
1 Cited Publications
Cat. No.: HY-107858
CAS No.: 93-03-8
Purity:  99.98%
Synonyms: 3,4-Dimethoxybenzyl alcohol
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
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1
1 Cited Publications
Cat. No.: HY-W075699
CAS No.: 73202-95-6
Synonyms: Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex
Target:  

MOFs

Research Areas:  

Others

Mn-TCPP(Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex) is a metal-organic framework (MOF).
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Cat. No.: HY-109110
CAS No.: 435327-40-5
Purity:  96.02%
Synonyms: GC-4419; M-40419
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
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Cat. No.: HY-W102714
CAS No.: 482-54-2
Synonyms: CDTA
Research Areas:  

Neurological Disease

1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
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Cat. No.: HY-132188
CAS No.: 114995-15-2
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .
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Cat. No.: HY-130574
CAS No.: 219818-60-7
Purity:  ≥95.0%
Synonyms: BMX-010 chloride
Research Areas:  

Cancer

MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer .
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Cat. No.: HY-W094492
CAS No.: 6156-78-1
Synonyms: manganese(Ii) acetate tetrahydrate
Research Areas:  

Others

Manganese acetate tetrahydrate (Manganese (II) acetate tetrahydrate) is a manganese (II) salt precursor that can be used in research related to material synthesis. Manganese acetate tetrahydrate can be used to synthesize manganese (III) acetate dihydrate via potassium permanganate oxidation, chlorine oxidation or anodic oxidation. Manganese acetate tetrahydrate serves as a precursor for the synthesis of manganese nanoparticles with antibacterial activity against Escherichia coli and Staphylococcus aureus. Manganese acetate tetrahydrate acts as a precursor for the synthesis of manganese-doped zinc oxide nanoparticles and manganese (III) oxide nanoparticles .
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Cat. No.: HY-W115799
CAS No.: 15375-84-5
Synonyms: Ethylenediaminetetraacetic acid (disodium manganese)
Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W103826
CAS No.: 32195-55-4
Synonyms: 5,10,15,20-Tetraphenyl-21H,23H-porphine manganese(III) chloride
Target:  

MOFs

Research Areas:  

Others

(5,10,15,20-Tetraphenylporphinato)manganese(III) chloride (5,10,15,20-Tetraphenyl-21H,23H-porphine Manganese(III) chloride) is an organic compound with catalytic capabilities .
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Cat. No.: HY-Y1369C
CAS No.: 10034-96-5
Synonyms: Manganous sulfate monohydrate, for cell culture
Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .
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Cat. No.: HY-W010854
CAS No.: 72003-83-9
Synonyms: dADP disodium
2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type .
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Cat. No.: HY-W010488
CAS No.: 79-40-3
Dithiooxamide (Rubeanic Acid) is a selective chelating agent and sulfur-containing analog of Oxamide. Dithiooxamide forms stable chelates with various metal ions (such as lead, iron, cadmium, manganese, and aluminum), which can be separated, enriched, and detected by adsorption on solid adsorbents or electrode surfaces .
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Cat. No.: HY-D0948
CAS No.: 1562-90-9
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
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Cat. No.: HY-119062
CAS No.: 681245-85-2
Target:  

MetAP CDK

Research Areas:  

Cancer

A-800141 is an orally active, selective, sulfonamide-based MetAP2 inhibitor (IC50=12 nM) that binds reversibly to MetAP2 and interacts with its manganese ions. A-800141 induces the production of N-terminal methionine-unprocessed GAPDH variants, which in turn triggers G1-phase cell cycle arrest, elevates p21 levels, and reduces the levels of phosphorylated Rb and total cyclin A. A-800141 exhibits anti-angiogenic and tumor growth inhibitory effects, and produces synergistic effects when combined with cytotoxic inhibitors or BCL-2 inhibitors. A-800141 has been widely used in scientific research related to B-cell lymphoma, neuroblastoma, prostate cancer, colon cancer, melanoma and other fields .
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Cat. No.: HY-W854721
CAS No.: 120389-54-0
Synonyms: manganese(III) Protoporphyrin IX Chloride
Target:  

Heme Oxygenase (HO)

Research Areas:  

Metabolic Disease

Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
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