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manganese

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53

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9

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Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109521A

    manganese(Ⅱ) chloride tetrahydrate, molecular biology grade,≥99.0% (KT)

    Biochemical Assay Reagents Histone Acetyltransferase HDAC Neurological Disease
    Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.
    Manganese chloride tetrahydrate, molecular biology grade,≥99.0% (KT)
  • HY-W019894
    Manganese chloride
    1 Publications Verification

    manganese dichloride

    Biochemical Assay Reagents Apoptosis mTOR Cardiovascular Disease Neurological Disease
    Manganese chloride is an orally active MRI liver contrast agent. Manganese chloride induces Apoptosis and activates the mTOR signaling pathway. Manganese chloride induces cognitive impairment, promotes hematopoietic recovery, and reduces radiation-induced bone marrow and brain damage. It can be used for the study of renal impairment .
    Manganese chloride
  • HY-109110

    GC-4419; M-40419

    Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
    Avasopasem manganese
  • HY-W102714

    CDTA

    Biochemical Assay Reagents Neurological Disease
    1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
    1,2-Cyclohexylenedinitrilotetraacetic acid
  • HY-13336
    Imisopasem manganese
    2 Publications Verification

    M40403; GC4403

    SOD Cancer
    Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.
    Imisopasem manganese
  • HY-B0885
    Econazole
    5 Publications Verification

    (±)-Econazol

    Fungal Bacterial Calcium Channel Cytochrome P450 Infection Metabolic Disease
    Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .
    Econazole
  • HY-107858
    Veratryl alcohol
    1 Publications Verification

    3,4-Dimethoxybenzyl alcohol

    Endogenous Metabolite Bacterial Infection
    Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
    Veratryl alcohol
  • HY-132188

    Endogenous Metabolite Others
    Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .
    Manganese peroxidase
  • HY-W001583
    Manganese(salen) chloride
    1 Publications Verification

    EUK-8

    Reactive Oxygen Species (ROS) Cardiovascular Disease
    Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine .
    Manganese(salen) chloride
  • HY-130574

    BMX-010 chloride

    Reactive Oxygen Species (ROS) Cancer
    MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer .
    MnTE-2-PyP chloride
  • HY-W094492

    manganese(Ii) acetate tetrahydrate

    Biochemical Assay Reagents Others
    Manganese acetate tetrahydrate (Manganese(Ii) acetate tetrahydrate) is a kind of biological materials or organic compounds that are widely used in life science research .
    Manganese acetate tetrahydrate
  • HY-W115799

    Ethylenediaminetetraacetic acid (disodium manganese)

    Environmental Pollutants Biochemical Assay Reagents Others
    Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    EDTA (disodium manganese)
  • HY-W103826

    5,10,15,20-Tetraphenyl-21H,23H-porphine manganese(III) chloride

    MOFs Others
    (5,10,15,20-Tetraphenylporphinato)manganese(III) chloride (5,10,15,20-Tetraphenyl-21H,23H-porphine Manganese(III) chloride) is an organic compound with catalytic capabilities .
    (5,10,15,20-Tetraphenylporphinato)manganese(III) chloride
  • HY-Y1369C

    Manganous sulfate monohydrate, for cell culture

    Biochemical Assay Reagents Others
    Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .
    Manganese sulfate monohydrate, for cell culture
  • HY-W010488

    Biochemical Assay Reagents Others
    Dithiooxamide (Rubeanic Acid) is a selective chelating agent and sulfur-containing analog of Oxamide. Dithiooxamide forms stable chelates with various metal ions (such as lead, iron, cadmium, manganese, and aluminum), which can be separated, enriched, and detected by adsorption on solid adsorbents or electrode surfaces .
    Dithiooxamide
  • HY-D0948

    Fluorescent Dye Infection
    Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
    Celestine Blue
  • HY-119062

    MetAP CDK Cancer
    A-800141 is an orally active, selective, sulfonamide-based MetAP2 inhibitor (IC50=12 nM) that binds reversibly to MetAP2 and interacts with its manganese ions. A-800141 induces the production of N-terminal methionine-unprocessed GAPDH variants, which in turn triggers G1-phase cell cycle arrest, elevates p21 levels, and reduces the levels of phosphorylated Rb and total cyclin A. A-800141 exhibits anti-angiogenic and tumor growth inhibitory effects, and produces synergistic effects when combined with cytotoxic inhibitors or BCL-2 inhibitors. A-800141 has been widely used in scientific research related to B-cell lymphoma, neuroblastoma, prostate cancer, colon cancer, melanoma and other fields .
    A-800141
  • HY-W854721

    manganese(III) Protoporphyrin IX Chloride

    Heme Oxygenase (HO) Metabolic Disease
    Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
    Mn(III) Protoporphyrin IX chloride
  • HY-132829

    GC4711

    Reactive Oxygen Species (ROS) Cancer
    Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .
    Rucosopasem manganese
  • HY-W787537

    LBB

    Biochemical Assay Reagents Others
    Leucoberbelin blue I (LBB) is a leuco base that is oxidized by manganese through a hydrogen atom transfer reaction forming a colored complex. Leucoberbelin blue I can be used to quantify or confirm the Mn (II) oxides formation .
    Leucoberbelin blue I
  • HY-179571

    PPTD

    Reactive Oxygen Species (ROS) Ferroptosis Cancer
    ZIP 14-IN-1 (PPTD) is a selective and orally active ZIP14 inhibitor. ZIP 14-IN-1 inhibits ZIP14 while sparing ZIP8 (SLC39A8). ZIP 14-IN-1 efficiently blocks ZIP14-mediated uptake of multiple divalent metals (zinc, iron, manganese and cadmium). ZIP 14-IN-1 binds to a pocket formed at the dimer interface of ZIP14, obstructing the metal transport pathway. ZIP 14-IN-1 effectively reverses the consequent elevation of reactive oxygen species (ROS) and lipid peroxidation, attenuating metal-induced cytotoxicity. ZIP 14-IN-1 can be uses for cancer cachexia research .
    ZIP14-IN-1
  • HY-D1229

    Fluorescent Dye Others
    Pigment Red 48:4 is a manganese-complex dye that can be used in printing ink applications and paint systems.
    Pigment Red 48:4
  • HY-19548

    Arginase Endocrinology
    BEC, an arginine analogue, is a slow-binding competitive inhibitor of the binuclear manganese metalloenzyme arginase. BEC enhances substrate flux to NO synthase, thereby enhancing NO-dependent smooth muscle relaxation in the corpus cavernosum, and enhances penile erection .
    BEC
  • HY-B0885R

    (±)-Econazol (Standard)

    Reference Standards Fungal Bacterial Calcium Channel Cytochrome P450 Infection Metabolic Disease
    Econazole (Standard) ((±)-Econazol (Standard)) is the analytical standard of Econazole (HY-B0885). This product is intended for research and analytical applications. Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .
    Econazole (Standard)
  • HY-137356R

    Fungal Reference Standards Infection
    Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries .
    Prochloraz manganese (Standard)
  • HY-137356

    Fungal Infection
    Prochloraz manganese is an antifungal agent, and is used in agricultural industries .
    Prochloraz manganese
  • HY-W134021

    Biochemical Assay Reagents Others
    Manganese dihydrogen phosphate is a kind of biological materials or organic compounds that are widely used in life science research .
    Manganese dihydrogen phosphate
  • HY-12764R

    GTPL5846 (Standard)

    Reference Standards GPR84 ERK Bacterial Antibiotic Inflammation/Immunology
    Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries .
    6-OAU (Standard)
  • HY-N11583

    Jasmololon

    Others Others
    Jasmololone (compound 1c) is a reduced compound that can be oxidized by manganese dioxide to form the corresponding diketone .
    Jasmololone
  • HY-W102714R

    CDTA (Standard)

    Biochemical Assay Reagents Reference Standards Neurological Disease
    1,2-Cyclohexylenedinitrilotetraacetic acid (Standard) is the analytical standard of 1,2-Cyclohexylenedinitrilotetraacetic acid (HY-W102714). This product is intended for research and analytical applications. 1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
    1,2-Cyclohexylenedinitrilotetraacetic acid (Standard)
  • HY-157359

    Biochemical Assay Reagents Others
    Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
    Bacterial Organophosphorus Medium
  • HY-P11145

    Influenza Virus Infection Inflammation/Immunology
    Influenza HA (529-537) is the amino acid sequence (IYATVAGSL) at positions 529-537 of the hemagglutinin (HA) of the influenza A virus. Influenza HA (529-537) can be recognized by three different specificities (H1-specific, H2-specific, H1/H2 cross-reactive) of CD8 + cytotoxic T-lymphocyte (CTL) clones. Influenza HA (529-537) can be used to understand T-cell immune specificity and to design new vaccines .
    Influenza HA (529-537)
  • HY-B0885S

    (±)-Econazol-d6

    Isotope-Labeled Compounds Fungal Bacterial Calcium Channel Cytochrome P450 Infection Metabolic Disease
    Econazole-d6 ((±)-Econazol-d6) is the deuterium labeled Econazole (HY-B0885). Econazole is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .
    Econazole-d6
  • HY-W738271

    3,4-Dimethoxybenzyl alcohol-13C

    Isotope-Labeled Compounds Bacterial Endogenous Metabolite Infection
    Veratryl alcohol- 13C (3,4-Dimethoxybenzyl alcohol- 13C) is the 13C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .
    Veratryl alcohol-13C
  • HY-138185

    SF 2738A

    Bacterial Apoptosis Cancer
    Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs=6.25 and 100 μg/mL) and fungi (MICs=12.5-100 μg/mL). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC50s=0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC50=56.6 μM) but not MDA-MD-231 breast cancer cells (IC50=>100 μM). Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions.3 Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae in a model of neuronal cell death induced by all-trans retinoic acid.
    Collismycin A
  • HY-132188A

    Biochemical Assay Reagents Metabolic Disease
    Manganese Peroxidase, Nematoloma frowardii (EC 1.11.1.13) is a hemecontaining glycoprotein that is produced by ligninolytic basidiomycetes. It requires hydrogen peroxide as an oxidant. Manganese Peroxidase, Nematoloma frowardii (EC 1.11.1.13) oxidizes Mn2+ to Mn3+. Mn3+ oxidizes phenolic rings to phenoxy radicals which results in the decomposition of various compounds.
    Manganese Peroxidase, Nematoloma frowardii
  • HY-W112984

    Tetra(p-chlorophenylporphyrinato)manganese chloride

    MOFs Others
    meso-Tetrakis(4-chlorophenyl)porphyrin-Mn(III)chloride (Tetra(p-chlorophenylporphyrinato)manganese chloride) is a metal-organic framework (MOF).
    meso-​Tetrakis(4-​chlorophenyl)​porphyrin-​Mn(III)​chloride
  • HY-W441531

    Biochemical Assay Reagents
    2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is a transition metal compound with excellent catalytic activity. 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is widely used in photocatalytic reactions to improve reaction efficiency. 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is also used in the preparation of optical materials, giving the materials excellent light absorption properties. The biological activity of 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride has gradually attracted attention in the research of the medical field.
    2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride
  • HY-W112284

    Mnt4MPyP

    MOFs Others
    5,10,15,20-Tetra(1-methyl-4-pyridyl)porphyrin manganese (Mnt4MPyP) is a metal-organic framework (MOF).
    5,10,15,20-Tetra(1-methyl-4-pyridyl)porphyrin manganese
  • HY-W456558

    MOFs Others
    (SP-4-1)-[5,10,15,20-Tetrakis(4-methylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese is a metal-organic framework (MOF).
    (SP-4-1)-[5,10,15,20-Tetrakis(4-methylphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese
  • HY-W456560

    MOFs Others
    (SP-4-1)-[5,10,15,20-Tetrakis(4-methoxyphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese is a metal-organic framework (MOF).
    (SP-4-1)-[5,10,15,20-Tetrakis(4-methoxyphenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese
  • HY-W113009

    meso-Tetratolylporphyrin-Mn(III)chloride

    MOFs Others
    5,?10,?15,?20-?Tetra(4-?methylphenyl)?-?21H,?23H-?porphine manganese(III) chloride (meso-Tetratolylporphyrin-Mn(III)chloride) is a metal-organic framework (MOF).
    5,​10,​15,​20-​Tetra(4-​methylphenyl)​-​21H,​23H-​porphine manganese(III) chloride
  • HY-W855977

    MOFs Others
    (SP-5-12)-Chloro[5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese is a metal-organic framework (MOF).
    (SP-5-12)-Chloro[5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese
  • HY-W075699
    Mn-TCPP
    1 Publications Verification

    Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex

    MOFs Others
    Mn-TCPP(Benzoic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-, manganese complex) is a metal-organic framework (MOF).
    Mn-TCPP
  • HY-W111690

    Dilithium tetrachloromanganese(2-)

    Biochemical Assay Reagents Others
    Manganese(II) chloride bis(lithium chloride) complex solution,0.956 g/mL at 25 °C, 0.5M in THF (Dilithium tetrachloromanganese(2-)) is an inorganic coordination complex, commonly used as a dedicated homogeneous catalyst in organic synthesis and battery research .
    Manganese(II) chloride bislithium chloride complex solution,0.956 g/mL at 25 °C, 0.5M in THF
  • HY-182482

    MetAP Cancer
    SB-587094 is a MetAP-2 inhibitor. SB-587094 inhibits cobalt- and manganese-containing hMetAP2. SB-587094 inhibits endothelial cell proliferation. SB-587094 is applicable to cancer-related research .
    SB-587094
  • HY-125859H

    Biochemical Assay Reagents Metabolic Disease
    The transformation of industrial dyes by manganese peroxidases from Bjerkandera adusta is a manganese-independent reaction.
    Peroxidase, Bjerkandera adusta
  • HY-E70951A

    Arginase Others
    Arginase, Human (EC 3.5.3.1) is a manganese-containing enzyme, the last enzyme in the urea cycle, catalyzing the conversion of arginine to ornithine and urea.
    Arginase, Human
  • HY-E70951

    Arginase Metabolic Disease
    Arginase, Rat (EC 3.5.3.1) is a manganese-containing enzyme and the last enzyme in the urea cycle. Arginase catalyzes the conversion of arginine to ornithine and urea.
    Arginase, Rat
  • HY-P11577

    MMP Biochemical Assay Reagents Cancer
    TGGGPLGVARGKGGC is a polypeptide that can be specifically cleaved by MMP-9. TGGGPLGVARGKGGC modifies manganese dioxide supraparticles. TGGGPLGVARGKGGC can be used in the research of early cancer diagnosis .
    TGGGPLGVARGKGGC

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