72003-83-9
72003-83-9
Chemical Structure
2'-Deoxyadenosine 5'-di-phos-phate disodium
Synonym(s): dADP disodium
- No. CAS: 72003-83-9
- Formula:C10H13N5Na2O9P2
- Molecular Weight:455.17
IUPAC Name: sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate
InChIKey: QPOQRKUWBIAHBO-OJSHLMAWSA-L
SMILES: O[C@H]1C[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COP(OP(O)(O[Na])=O)(O[Na])=O
Biological Activity: 2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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2'-Deoxyadenosine 5'-di-phos-phate disodium | 95.0% | 2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type. | ||||||||||||||||||||
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5'-dAMPS | 5'-dAMPS is an analogue of 5'-dAMP and thus a potential substrate, competitive inhibitor or regulator of enzymes that interact with dAMP. | |||||||||||||||||||||
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2'-Deoxyadenosine-5'-triphosphate | 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. | |||||||||||||||||||||
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2'-Deoxyadenosine-5'-triphosphate trisodium | 98.0% | 2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency . | ||||||||||||||||||||
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3′-Deoxyadenosine 5′-diphosphate disodium | 3′-Deoxyadenosine 5′-diphosphate (3′-dADP) disodiumIt can be used to study various physiological processes such as energy metabolism and information transmission. | |||||||||||||||||||||
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Adenosine 5'-diphosphate disodium (Standard) | 99.86% | Adenosine 5'-diphosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-diphosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis. | ||||||||||||||||||||
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2'-Deoxyadenosine 5'-triphosphate disodium | 99.97% | 2'-Deoxyadenosine 5'-triphosphate disodium (5'-Dexoadenosine triphosphate disodium) is a nucleotide with important biological activities and can serve as a substrate for a variety of polymerases, including DNA polymerases and reverse transcriptases. 2'-Deoxyadenosine 5'-triphosphate disodium plays a key role in DNA synthesis and reverse transcription. 2'-Deoxyadenosine 5'-triphosphate disodium is also widely used in in vitro reactions in molecular biology research. | ||||||||||||||||||||
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2'-Deoxyadenosine-5'-monophosphate | 99.60% | 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage. | ||||||||||||||||||||
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2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium | 2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage. | |||||||||||||||||||||
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2′-Deoxyadenosine 5′-monophosphate disodium | 99.31% | 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage. | ||||||||||||||||||||
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Deoxyadenosine diphosphate sodium | Deoxyadenosine diphosphate sodium is a nucleoside diphosphate, in which the nucleoside is deoxyadenosine. Deoxyadenosine diphosphate sodium participates in DNA synthesis and repair. Deoxyadenosine diphosphate sodium acts as the inhibitor of polynucleotide phosphorylase, interfers with the polymerization of ADP and CDP. | |||||||||||||||||||||
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References
- [1]. Deutscher MP, et al. Synthesis and degradation of poly(A) in permeable cells of Escherichia coli. The Journal of biological chemistry. 1978 Aug 25;253(16):5579-84. [Content Brief]
- [2]. Fazakerley GV, et al. Determination of the interaction of ADP and dADP with copper(II), manganese(II) and lanthanide(III) ions by nuclear-magnetic-resonance spectroscopy. European journal of biochemistry. 1979 Feb 01;93(3):535-43. [Content Brief]
