72003-83-9
Chemical Structure
2'-Deoxyadenosine 5'-di-phos-phate disodium
Synonym(s): dADP disodium
- CAS No.: 72003-83-9
- Formula:C10H13N5Na2O9P2
- Molecular Weight:455.17
IUPAC Name: sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate
InChIKey: QPOQRKUWBIAHBO-OJSHLMAWSA-L
SMILES: O[C@H]1C[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COP(OP(O)(O[Na])=O)(O[Na])=O
Biological Activity: 2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2'-Deoxyadenosine 5'-di-phos-phate disodium | 95.0% | 2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type. | ||||||||||||||||||||
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References
- [1]. Deutscher MP, et al. Synthesis and degradation of poly(A) in permeable cells of Escherichia coli. The Journal of biological chemistry. 1978 Aug 25;253(16):5579-84. [Content Brief]
- [2]. Fazakerley GV, et al. Determination of the interaction of ADP and dADP with copper(II), manganese(II) and lanthanide(III) ions by nuclear-magnetic-resonance spectroscopy. European journal of biochemistry. 1979 Feb 01;93(3):535-43. [Content Brief]
