19 Results for "

methylated form

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "methylated form" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-113354
CAS No.: 584-85-0
Purity:  99.85%
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine has blood-brain barrier permeability, and improves memory functions in Alzheimer's disease (AD)-model mice .
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Cat. No.: HY-153080
Purity:  94.6%
Target:  

Fluorescent Dye mRNA

Research Areas:  

Others

Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a modified form of firefly luciferase mRNA, which is N1-methylated pseudo uridine (N1-Me-Pseudo UTP). Firefly Luciferase mRNA (N1-Me-Pseudo UTP) is a commonly used reporter molecule in biomedical and mRNA research and its core function is to rapidly and quantitatively monitor the expression and delivery efficiency of mRNA through the emission of light signals .
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Cat. No.: HY-Y1078
CAS No.: 4637-24-5
Synonyms: N-Dimethoxymethyl-N,N-dimethylamine
Research Areas:  

Others

DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .
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Cat. No.: HY-113354S
CAS No.: 1201658-81-2
Purity:  99.38%
Anserine-d4 is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .
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Cat. No.: HY-113046S
Purity:  ≥98.0%
Synonyms: 5-Methyl THF-13C5; 5-MTHF-13C,d5
5-Methyltetrahydrofolic acid- 13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid .
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Cat. No.: HY-P10463
Research Areas:  

Cancer

ssK36 is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2), and ssK36 is designed for the SETD2 protein, a specific PKMT. ssK36 is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. ssK36 can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency .
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Cat. No.: HY-P10463A
Research Areas:  

Cancer

ssK36 TFA is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2) , and ssK36 TFA is designed for the SETD2 protein, a specific PKMT. ssK36 TFA is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. ssK36 TFA can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 TFA can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency .
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Cat. No.: HY-W091169
CAS No.: 63989-87-7
Synonyms: 2-((Methylamino)methyl)phenol hydrochloride
N-Methyl-2-HOBA (2-((Methylamino)methyl)phenol) hydrochloride is a methylated form of the isoketal scavenger 2-HOBA (HY-34350). N-Methyl-2-HOBA hydrochloride can be used as a negative control for the activity of 2-HOBA in a mouse model of hypertension .
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Cat. No.: HY-W006395R
CAS No.: 1122-47-0
1-Methylcytosine is a methylated form of the DNA base cytosine and used as a nucleobase of hachimoji DNA, in which it pairs with Isoguanine .
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Cat. No.: HY-113354R
CAS No.: 584-85-0
Anserine (Standard) is the analytical standard of Anserine. This product is intended for research and analytical applications. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
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Cat. No.: HY-113354S1
Anserine-d4 hydrochloride is the deuterium labeled Anserine (HY-113354). Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .
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Cat. No.: HY-147740
CAS No.: 70492-21-6
Research Areas:  

Cancer

WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslinkforms covalent adducts at CpG sequences and exhibits a preference for methylated CpG sites. Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks. Formaldehyde-activated WEHI-150 shows Concentration-dependent transcription blockages. WEHI-150 can mediate covalent adducts that are independent of interactions with the N-2 of guanine and is capable of adduct formation at novel DNA sequences .
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Cat. No.: HY-E71338
Research Areas:  

Others

γ-Glutamylanilide synthase (EC 6.3.1.18) requires Mg2+. The enzyme, characterized from the bacterium Acinetobacter sp. YAA, catalyses the first step in the degradation of aniline. It can also accept chlorinated and methylated forms of aniline, preferrably in the o-and p-positions.
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Cat. No.: HY-W013187
CAS No.: 21028-20-6
Research Areas:  

Others Cancer

3-Methylcytidine methosulfate is the methosulfate form of the N3-methylated cytidine analog 3-methylcytidine (HY-111645). 3-Methylcytidine methosulfate blocks the N3 site of cytidine via N3 methylation, generates steric hindrance, and reduces the basicity of the C4 amino group, thereby weakening its interaction with the allosteric site of E. coli ATCase. 3-Methylcytidine methosulfate can be used in studies of ATCase nucleotide recognition, allosteric regulation, and cytidine methylation .
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Cat. No.: HY-P11865
CAS No.: 2379342-67-1
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

Ac-ATS010-KE is a selective polypeptide inhibitor of caspase-3. Ac-ATS010-KE protects cells from FasL-induced apoptosis. The unmethylated form of Ac-ATS010-KE exhibits better cell viability than the fully methylated form. Ac-ATS010-KE can be used in research on cancers such as colorectal cancer and the development of caspase-3-targeted molecular probes .
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Cat. No.: HY-107852
CAS No.: 17040-19-6
Target:  

Insecticide

Research Areas:  

Infection

Demeton-S-methyl sulfone is an organophosphorus insecticide metabolite.Demeton-S-methyl sulfone serves as a substrate for metabolic breakdown.Demeton-S-methyl sulfone forms via oxidation of demeton S-methyl sulfoxide in sugar-beet cell suspension cultures.Demeton-S-methyl sulfone undergoes thioester bond cleavage, producing ethanethiols that convert into S-methylated compounds or S-glucosides .
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Cat. No.: HY-186081
CAS No.: 1357570-22-9
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Ramiprilat acyl-β-D-glucuronide is an acyl glucuronide metabolite of Ramiprilat (HY-B0279). Ramiprilat acyl-β-D-glucuronide undergoes methylation on its glucuronic acid moiety during solid phase extraction with strong cation exchanger cartridges, forming a methylated derivative. Ramiprilat acyl-β-D-glucuronide undergoes in-source conversion to Ramiprilat in mass spectrometry, with conversion extent proportional to declustering potential voltage .
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Cat. No.: HY-N20741
CAS No.: 615275-47-3
7-O-Methylpuerarin is a 7-O-methylated derivative of puerarin that serves as a substrate for oxidation reactions. The glucosyl moiety of 7-O-Methylpuerarin undergoes regioselective oxidation to form 3''-oxo-7-O-methylpuerarin. 7-O-Methylpuerarin is a byproduct generated during the demethylation of 7,4'-di-O-methylpuerarin, and it can be oxidized by D3dgpA to produce 3''-oxo-7-O-methylpuerarin. 7-O-Methylpuerarin is applicable to studies related to the selective oxidation of glycoside oxidases .
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Cat. No.: HY-P11652
CAS No.: 857267-11-9
Research Areas:  

Others

Cardiogen is a short biologically active peptide (Ala-Glu-Asp-Arg) that does not bind single-stranded deoxyribooligonucleotides, slightly quenches fluorescence of some double-stranded deoxyribooligonucleotides, strongly quenches fluorescence of methylated and unmethylated λ phage DNA-ethidium bromide complexes .
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