7-O-Methylpuerarin
7-O-Methylpuerarin is a 7-O-methylated derivative of puerarin that serves as a substrate for oxidation reactions. The glucosyl moiety of 7-O-Methylpuerarin undergoes regioselective oxidation to form 3''-oxo-7-O-methylpuerarin. 7-O-Methylpuerarin is a byproduct generated during the demethylation of 7,4'-di-O-methylpuerarin, and it can be oxidized by D3dgpA to produce 3''-oxo-7-O-methylpuerarin. 7-O-Methylpuerarin is applicable to studies related to the selective oxidation of glycoside oxidases.
For research use only. We do not sell to patients.
- CAS No.: 615275-47-3
- Formula: C22H22O9
- Molecular Weight:430.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
7-O-Methylpuerarin is formed in a small amount when 7,4′-di-O-methylpuerarin is treated with Me3SiI under reflux in chloroform for 4 days, and its C-7 methoxy group does not undergo further demethylation[1].
7-O-Methylpuerarin is obtained in 39% yield when 7,4′-di-O-methylpuerarin is treated with Me3SiI under reflux in acetonitrile for 5 days[1].
7-O-Methylpuerarin (1 mM) is regioselectively oxidized in vitro by purified D3dgpA to afford 3″-Oxo-7-O-methylpuerarin[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 615275-47-3
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Molecular Weight 430.40
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Formula C22H22O9
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SMILES
COC1=CC=C(C(C(C2=CC=C(C=C2)O)=CO3)=O)C3=C1[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yasuda T, et al. Urinary and biliary metabolites of puerarin in rats. Biol Pharm Bull. 1995 Feb;18(2):300-3. doi: 10.1248/bpb.18.300. PMID: 7742802. [Content Brief]
[2]. Kim H, et al. Glycoside-metabolizing oxidoreductase D3dgpA from human gut bacterium. Frontiers in bioengineering and biotechnology. 2024;12:1413854. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
7-O-Methylpuerarin Related Classifications
HY-N20741 Related Classifications
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