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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
microtubule affinity regulating kinase
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "microtubule affinity regulating kinase" in MCE Product Catalog:
3
3 Cited Publications
PCC0208017 is a microtubule affinity regulating kinases (MARK3/MARK4) inhibitor with IC50s of 1.8 and 2.01 nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC50s of 31.4 and 33.7 nM, respectively. PCC0208017 suppresses glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability .
1
1 Cited Publications
MARK4 inhibitor 1 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis .
Research Areas:
MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 5 nM.
Research Areas:
MARK-IN-4 (Compound 18) is a MARK inhibitor with an IC50 of 1 nM. MARK-IN-4 is applicable to Alzheimer's disease research .
Target:
Research Areas:
MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0.25 nM.
Cat. No.: HY-W070306
CAS No.: 1207836-10-9
Cat. No.: HY-P701808
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MARK4; FLJ90097; Prev. MARKL1; Non-Specific Serine/Threonine Protein kinase; MAP/microtubule affinity-regulating kinase 4; Epididymis Secretory Sperm Binding Protein; KIAA1860; MARK4 Serine/Threonine Protein kinase; PAR-1D; MARKL1L; MAP/microtubule affinity-regulating kinase Like 1; MARK4L; Nbla00650; MARK4S; microtubule affinity regulating kinase 4; MAP/microtubule affinity-regulating kinase-Like 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P701809
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MARK4; FLJ90097; Prev. MARKL1; Non-Specific Serine/Threonine Protein kinase; MAP/microtubule affinity-regulating kinase 4; Epididymis Secretory Sperm Binding Protein; KIAA1860; MARK4 Serine/Threonine Protein kinase; PAR-1D; MARKL1L; MAP/microtubule affinity-regulating kinase Like 1; MARK4L; Nbla00650; MARK4S; microtubule affinity regulating kinase 4; MAP/microtubule affinity-regulating kinase-Like 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P701806
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MARK1; PAR1 Homolog C; microtubule affinity regulating kinase 1; Par1c; MAP/microtubule affinity-regulating kinase 1; MAP/microtubule affinity-regulating kinase 1 Isoform A; MARK; Non-Specific Serine/Threonine Protein kinase; Serine/Threonine-Protein kinase MARK1; KIAA1477; PAR-1C; Par-1c
Species:
Human
Source:
E. coli
Cat. No.: HY-P701807
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MARK1; PAR1 Homolog C; microtubule affinity regulating kinase 1; Par1c; MAP/microtubule affinity-regulating kinase 1; MAP/microtubule affinity-regulating kinase 1 Isoform A; MARK; Non-Specific Serine/Threonine Protein kinase; Serine/Threonine-Protein kinase MARK1; KIAA1477; PAR-1C; Par-1c
Species:
Human
Source:
E. coli
Cat. No.: HY-P82359
Synonyms: ELKL motif kinase 1 antibody;
ELKL motif kinase antibody;
EMK-1 antibody;
EMK1 antibody;
MAP/microtubule affinity regulating kinase 2 antibody;
MAP/microtubule affinity-regulating kinase 2 antibody;
Mark2 antibody;
MARK2_HUMAN antibody;
MGC99619 antibody;
PAR 1 antibody;
Par 1b antibody;
PAR1 homolog antibody;
Par1b antibody;
Ser/Thr protein kinase PAR 1B antibody;
Serine/threonine protein kinase EMK antibody;
Serine/threonine protein kinase MARK2 antibody;
Serine/threonine-protein kinase MARK2 antibody;
Cat. No.: HY-101934R
CAS No.: 1314893-26-9
Target:
Research Areas:
MARK-IN-2 (Standard) is the analytical standard of MARK-IN-2 (HY-101934). This product is intended for research and analytical applications. MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 5 nM.
Cat. No.: HY-P706073
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MARK4; FLJ90097; Prev. MARKL1; Non-Specific Serine/Threonine Protein kinase; MAP/microtubule affinity-regulating kinase 4; Epididymis Secretory Sperm Binding Protein; KIAA1860; MARK4 Serine/Threonine Protein kinase; PAR-1D; MARKL1L; MAP/microtubule Affini
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702749
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TAOK1; Serine/Threonine-Protein kinase TAO1; TAO kinase 1; Prostate-Derived STE20-Like kinase 2; MAP3K16; kinase From Chicken Homolog B; HTAOK1; FLJ14314; HKFC-B; PSK-2; MARKK; microtubule affinity regulating kinase kinase; PSK2; Serine/Threonine Protein
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P82405
Synonyms: C-TAK1 antibody;
Cdc25C associated protein kinase 1 antibody;
Cdc25C-associated protein kinase 1 antibody;
cTAK1 antibody;
ELKL motif kinase 2 antibody;
EMK-2 antibody;
Emk2 antibody;
ETK 1 antibody;
KIAA4230 antibody;
KP78 antibody;
MAP microtubule affinity regulating kinase 3 antibody;
MAP/microtubule affinity-regulating kinase 3 antibody;
Mark3 antibody;
MARK3_HUMAN antibody;
Par 1a antibody;
PAR1A antibody;
Protein kinase STK10 antibody;
Ser/Thr protein kinase PAR-1 antibody;
Serine threonine protein kinase p78 antibody;
Serine/threonine-protein kinase p78 antibody;
SerThr protein kinase PAR 1 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
