2. Search Result
Search Result
Results for "

naphthalene derivatives

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

2

Biochemical Assay Reagents

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15417
    ML-7 hydrochloride
    20+ Cited Publications

    		 Myosin YAP Cancer
    ML-7 hydrochloride is a naphthalene sulphonamide derivative, potently inhibits MLCK (IC50=300 nM). ML-7 hydrochloride also inhibits YAP/TAZ.
    ML-7 hydrochloride
  • HY-W016288
    Naphthalene-2,3-dicarboxaldehyde
    1 Publications Verification

    2,3-naphthalenedicarboxaldehyde; naphthalene-2,3-dialdehyde

    		 Fungal Infection
    Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
    Naphthalene-2,3-dicarboxaldehyde
  • HY-148012
    SOP1812

    QN-302

    		 G-quadruplex Cancer
    SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with anti-tumor activity. SOP1812 binds to quadruplex arrangements (G4s), and down-regulates several cancer gene pathways. SOP1812 shows great affinity to hTERT G4 and HuTel21 G4 with KD values of 4.9 and 28.4 nM, respectively. SOP1812 can be used for the research of cancer .
    SOP1812
  • HY-32126
    1-Fluoronaphthalene

    		Drug Intermediate Others
    1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene
  • HY-W005148
    3-Amino-2-naphthoic acid

    		Biochemical Assay Reagents Others
    3-Amino-2-naphthoic acid is a derivative of naphthalene and can be used to synthesize other compounds. 3-Amino-2-naphthoic acid is commonly used as the base material for synthesizing various dyes and pigments. 3-Amino-2-naphthoic acid has been developed as a "turn-on" fluorescence probe for the specific detection of the cyanate anion (CNO -) .
    3-Amino-2-naphthoic acid
  • HY-W016288R
    Naphthalene-2,3-dicarboxaldehyde (Standard)

    2,3-naphthalenedicarboxaldehyde (Standard); naphthalene-2,3-dialdehyde (Standard)

    		 Fungal Reference Standards Infection
    Naphthalene-2,3-dicarboxaldehyde (Standard) is the analytical standard for Naphthalene-2,3-dicarboxaldehyde (HY-W016288). This product is for research and analytical applications. Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
    Naphthalene-2,3-dicarboxaldehyde (Standard)
  • HY-W017241
    1-Naphthalenemethanol

    1-Hydroxymethylnaphthalene

    		 Bacterial Biochemical Assay Reagents Infection
    1-Naphthalenemethanol is a hydroxyl-substituted naphthalene derivative. 1-Naphthalenemethanol can be extracted from the root of Annona senegalensis. 1-Naphthalenemethanol is a photolysis product of 1-napthaleneacetic acid. 1-Naphthalenemethanol, together with PAPS, provides some protection against the irreversible inactivation of AST IV caused by N-OH-2AF. 1-Naphthalenemethanol can be used in antibacterial research .
    1-Naphthalenemethanol
  • HY-174301
    USP7-IN-18

    		Deubiquitinase DNA Methyltransferase MDM-2/p53 Cancer
    USP7-IN-18 is a naphthalene derivative. USP7-IN-18 is a selective USP7 inhibitor (IC50 : 130.9 nM), with no or very weak inhibition of the other 8 DUBs including USP47. USP7-IN-18 specifically binds to the catalytic domain of USP7, blocking its deubiquitinase activity. USP7-IN-18 causes degradation of the oncogenic proteins MDM2 and DNMT1, and also degrades the novel target PCLAF. USP7-IN-18 activates the p53-p21 pathway. USP7-IN-18 exerts anti-tumor effects in colon cancer animal models and reshapes the tumor immune microenvironment. USP7-IN-18 achieves both direct cytotoxic and immune-synergistic anti-tumor actions.
    USP7-IN-18
  • HY-32126R
    1-Fluoronaphthalene (Standard)

    		Adrenergic Receptor Serotonin Transporter Reference Standards Others
    1-Fluoronaphthalene (Standard) is the analytical standard of 1-Fluoronaphthalene. This product is intended for research and analytical applications. 1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
    1-Fluoronaphthalene (Standard)
  • HY-W128203
    1-Naphthyl β-D-glucopyranoside

    		Biochemical Assay Reagents Others
    1-Naphthyl β-D-glucopyranoside is a naphthalene sugar derivative that can be used in glycobiology research.
    1-Naphthyl β-D-glucopyranoside
  • HY-105460
    TEI-6472

    		Histamine Receptor Inflammation/Immunology
    TEI-6472, a naphthalene derivative, can suppress IgE responses both in vitro and in vivo. TEI-6472 causes significant inhibition of FceRI-mediated histamine release .
    TEI-6472
  • HY-W017241R
    1-Naphthalenemethanol (Standard)

    1-Hydroxymethylnaphthalene (Standard)

    		 Reference Standards Bacterial Biochemical Assay Reagents Infection
    1-Naphthalenemethanol (Standard) is the analytical standard of 1-Naphthalenemethanol (HY-W017241). This product is intended for research and analytical applications. 1-Naphthalenemethanol is a hydroxyl-substituted naphthalene derivative. 1-Naphthalenemethanol can be extracted from the root of Annona senegalensis. 1-Naphthalenemethanol is a photolysis product of 1-napthaleneacetic acid. 1-Naphthalenemethanol, together with PAPS, provides some protection against the irreversible inactivation of AST IV caused by N-OH-2AF. 1-Naphthalenemethanol can be used in antibacterial research .
    1-Naphthalenemethanol (Standard)
  • HY-N17439
    4-Ethoxy-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one

    		Glycosidase Metabolic Disease
    4-Ethoxy-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one is a naphthalene derivative and a weak α-glucosidase inhibitor. 4-Ethoxy-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one can be found in the leaves of Cyclocarya paliurus. 4-Ethoxy-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one can be used for the research of diabetes .
    4-Ethoxy-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one
  • HY-W087908
    1,3-Dimethylnaphthalene

    		Drug Derivative Others
    1,3-Dimethylnaphthalene is a Naphthalene (HY-Y0602) derivative. 1,3-Dimethylnaphthalene induces hatching of cod larvae .
    1,3-Dimethylnaphthalene
  • HY-W131305
    Naphthohydroquinone

    		Drug Intermediate Cancer
    Naphthohydroquinone is a compound featuring a naphthalene ring structure with two hydroxyl groups. Naphthohydroquinone exhibits significant cytotoxicity and antitumor activity in some of its derivatives .
    Naphthohydroquinone
  • HY-179593
    GM47-1

    		Bacterial Inflammation/Immunology
    GM47-1, a naphthalene scaffold derivative, is a potent mycolic acid transporter MmpL3 inhibitor exhibiting potent bactericidal activity against Mycobacterium abscessus (Mabs) with an MIC50 of 2.1 µM. GM47-1 targets MmpL3, disrupts cell wall integrity, and induces ATP leakage and uncouples respiration. GM47-1 can be used for Mycobacterium abscessus pulmonary disease (Mabs-PD) research .
    GM47-1

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: