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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
naphthalene derivatives
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "naphthalene derivatives" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-W016288
CAS No.: 7149-49-7
Synonyms: 2,3-naphthalenedicarboxaldehyde; naphthalene-2,3-dialdehyde
Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
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SOP1812 (QN-302) is a naphthalene diimide (ND) derivative with anti-tumor activity. SOP1812 binds to quadruplex arrangements (G4s), and down-regulates several cancer gene pathways. SOP1812 shows great affinity to hTERT G4 and HuTel21 G4 with KD values of 4.9 and 28.4 nM, respectively. SOP1812 can be used for the research of cancer .
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1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
Cat. No.: HY-W005148
CAS No.: 5959-52-4
Cat. No.: HY-W016288R
CAS No.: 7149-49-7
Synonyms: 2,3-naphthalenedicarboxaldehyde (Standard); naphthalene-2,3-dialdehyde (Standard)
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Naphthalene-2,3-dicarboxaldehyde (Standard) is the analytical standard for Naphthalene-2,3-dicarboxaldehyde (HY-W016288). This product is for research and analytical applications. Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
Cat. No.: HY-W017241
CAS No.: 4780-79-4
Synonyms: 1-Hydroxymethylnaphthalene
Category:
Natural Products other families Microorganisms Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-174301
CAS No.: 3052223-40-9
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USP7-IN-18 is a naphthalene derivative. USP7-IN-18 is a selective USP7 inhibitor (IC50 : 130.9 nM), with no or very weak inhibition of the other 8 DUBs including USP47. USP7-IN-18 specifically binds to the catalytic domain of USP7, blocking its deubiquitinase activity. USP7-IN-18 causes degradation of the oncogenic proteins MDM2 and DNMT1, and also degrades the novel target PCLAF. USP7-IN-18 activates the p53-p21 pathway. USP7-IN-18 exerts anti-tumor effects in colon cancer animal models and reshapes the tumor immune microenvironment. USP7-IN-18 achieves both direct cytotoxic and immune-synergistic anti-tumor actions.
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1-Fluoronaphthalene (Standard) is the analytical standard of 1-Fluoronaphthalene. This product is intended for research and analytical applications. 1-Fluoronaphthalene is an organofluorine compound derived from naphthalene derivatives and fluorinated aromatics. 1-Fluoronaphthalene can be used to synthesize LY248686, a potent inhibitor of serotonin and noradrenaline uptake .
Cat. No.: HY-W128203
CAS No.: 19939-82-3
Cat. No.: HY-120730
CAS No.: 13071-27-7
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DA 1686 is an orally active naphthalene derivative that induces bradycardia and mild hypotension. DA 1686 can be used in the study of arrhythmias .
Cat. No.: HY-105460
CAS No.: 151379-49-6
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TEI-6472, a naphthalene derivative, can suppress IgE responses both in vitro and in vivo. TEI-6472 causes significant inhibition of FceRI-mediated histamine release .
Cat. No.: HY-W017241R
CAS No.: 4780-79-4
Synonyms: 1-Hydroxymethylnaphthalene (Standard)
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Cat. No.: HY-N17439
CAS No.: 1799427-52-3
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Cat. No.: HY-W012566
CAS No.: 2243-62-1
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1,5-Naphthalenediamine is a naphthalene derivative. 1,5-Naphthalenediamine serves as a substrate for the detection and identification of trace molecules .
Cat. No.: HY-W087908
CAS No.: 575-41-7
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1,3-Dimethylnaphthalene is a Naphthalene (HY-Y0602) derivative. 1,3-Dimethylnaphthalene induces hatching of cod larvae .
Cat. No.: HY-W131305
CAS No.: 571-60-8
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Naphthohydroquinone is a compound featuring a naphthalene ring structure with two hydroxyl groups. Naphthohydroquinone exhibits significant cytotoxicity and antitumor activity in some of its derivatives .
Cat. No.: HY-179593
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GM47-1, a naphthalene scaffold derivative, is a potent mycolic acid transporter MmpL3 inhibitor exhibiting potent bactericidal activity against Mycobacterium abscessus (Mabs) with an MIC50 of 2.1 µM. GM47-1 targets MmpL3, disrupts cell wall integrity, and induces ATP leakage and uncouples respiration. GM47-1 can be used for Mycobacterium abscessus pulmonary disease (Mabs-PD) research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
