31 Results for "

nucleoside antibiotic

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "nucleoside antibiotic" in MCE Product Catalog:

174
174 Publications Verification
Cat. No.: HY-A0098
CAS No.: 11089-65-9
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .
loading...
    loading...
17
17 Cited Publications
Cat. No.: HY-N6733
CAS No.: 38966-21-1
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-K1054

MCE Blasticidin S, Sterile (10 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Blasticidin S is a peptidyl nucleoside antibiotic isolated from Streptomyces griseochromogenes. It acts by blocking hydrolysis of peptidyl-tRNA induced by release factors and inhibits peptide bond formation.

loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-122502
CAS No.: 30868-30-5
Purity:  98.18%
Synonyms: Pirazofurin
Pyrazofurin is an antitumor pyrimidine nucleoside analogue and a orotate-phosphoribosyltransferase inhibitor. Pyrazofurin inhibits cell proliferation and intracellular DNA synthesis by inhibiting uridine 5'-phosphate synthase. Pyrazofurin is also an antibiotic with a broad spectrum of antiviral activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-125650
CAS No.: 1566586-52-4
Purity:  ≥96.0%
Synonyms: PUM
Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC50 of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis .
loading...
    loading...
Cat. No.: HY-117260
CAS No.: 11033-22-0
Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity .
loading...
    loading...
Cat. No.: HY-152296
CAS No.: 56973-12-7
Research Areas:  

Infection

8-Methyladenosine is a modified adenosine nucleoside. Through methylation at the 8-position, 8-Methyladenosine confers bacterial resistance to five classes of antibiotics that bind to the ribosomal peptidyl transferase center. 8-Methyladenosine can be used in studies of antibiotic-resistant bacterial infections .
loading...
    loading...
Cat. No.: HY-102026
CAS No.: 6742-12-7
Purity:  ≥99.0%
Synonyms: NSC 102811
Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM. Formycin A shows antitumor and antiviral activities .
loading...
    loading...
Cat. No.: HY-124438
CAS No.: 55353-31-6
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Herbicidin A is an adenosine-derived nucleoside antibiotic, but also is a herbicide against dicotyledonous plants. Herbicidin A can be isolated from Streptomyces scopuliridis M40 .
loading...
    loading...
Cat. No.: HY-W011549
CAS No.: 60966-26-9
2'-Amino-2'-deoxyguanosine is a nucleoside antibiotic. 2'-Amino-2'-deoxyguanosine exhibits lethal activity against certain strains of Escherichia coli, with its antibacterial effect reversible by guanosine and other purine nucleosides. 2'-Amino-2'-deoxyguanosine can be used for the study of bacterial infection .
loading...
    loading...
Cat. No.: HY-127130
CAS No.: 87099-85-2
Research Areas:  

Infection Cancer

Spicamycin, an adenine nucleoside antibiotic with antifungal and antitumor activities. Spicamycin is also a potent inducer of differentiation of myeloid leukemia cells. Spicamycin induces apoptosis in NB4 cells via down-regulation of Bcl-2 expression and modulation of PML protein .
loading...
    loading...
Cat. No.: HY-101136
CAS No.: 66522-52-9
Synonyms: AT-265
Research Areas:  

Infection

Dealanylascamycin (AT-265) (Compound 2) is a nucleoside antibiotic. AT 265 is a carbonic anhydrase (CA) inhibitor, with Ki values of 167, 65.2, 234, and 143 nM for hCA I, hCA II, hCA IV, and hCA IX respectively. Dealanylascamycin is the active form of Ascamycin (HY-121071). Dealanylascamycin exhibits broad-spectrum antibacterial activity and is effective against pathogenic bacteria such as Xanthomonas citri (MIC = 0.4 μg/mL). Dealanylascamycin has high cytotoxicity .
loading...
    loading...
Cat. No.: HY-N14216
CAS No.: 22976-90-5
Target:  

Antibiotic Fungal

Polyoxin L is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
loading...
    loading...
Cat. No.: HY-N14208
CAS No.: 22976-87-0
Category:  

Microorganisms Antibiotics

Target:  

Antibiotic Fungal

Polyoxin E is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
loading...
    loading...
Cat. No.: HY-N14211
CAS No.: 23116-76-9
Polyoxin F is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
loading...
    loading...
Cat. No.: HY-N14213
CAS No.: 24695-54-3
Category:  

Microorganisms Antibiotics

Target:  

Antibiotic Fungal

Polyoxin H is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
loading...
    loading...
Cat. No.: HY-N15107
CAS No.: 34718-88-2
Target:  

Antibiotic Fungal

Polyoxin M is a nucleoside antifungal antibiotic and has significant effects on rice sheath blight .
loading...
    loading...
Cat. No.: HY-128514
CAS No.: 32388-21-9
Synonyms: Oxazinomycin
Minimycin (Oxazinomycin) is a nucleoside antibiotic with a broad-spectrum antibacterial activity. Minimycin has inhibitory effect on mouse Ehrlich ascites carcinoma, ascites type and solid type sarcoma-180 .
loading...
    loading...
Cat. No.: HY-N12498
CAS No.: 123970-01-4
Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. .
loading...
    loading...
Cat. No.: HY-N6733R
CAS No.: 38966-21-1
Aphidicolin (Standard) is the analytical standard of Aphidicolin. This product is intended for research and analytical applications. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
loading...
    loading...