123970-01-4
Chemical Structure
Aureonuclemycin
- CAS No.: 123970-01-4
- Formula:C16H19N5O9
- Molecular Weight:425.35
InChIKey: OJKCJHCMNLAGNV-LSXCWCRBSA-N
SMILES: O[C@]12[C@@](O[C@@H]([C@H]([C@@H]2O)O)C(O)=O)([H])C[C@]3([H])[C@]([C@H]([C@H](N4C5=NC=NC(N)=C5N=C4)O3)O)([H])O1
Biological Activity: Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. [1][2].
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Aureonuclemycin | Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. . | |||||||||||||||||||||
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References
- [1]. Pan HX, et al. Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity. Org Lett. 2019 Mar 1;21(5):1374-1378. [Content Brief]
- [2]. Wang W, et al. Antibacterial Activity of Aureonuclemycin Produced by Streptomyces aureus Strain SPRI-371[J]. Molecules, 2022, 27(15): 5041. [Content Brief]
