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Results for "

platinum(II)

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-105930
    Lobaplatin
    5 Publications Verification

    D-19466

    		 Apoptosis Caspase Bcl-2 Family Cancer
    Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. Lobaplatin can be used for research of cancer .
    Lobaplatin
  • HY-W075885
    trans-Platinum(II)diammine dichloride

    trans-platinumdiamminedichloride

    		 DNA Alkylator/Crosslinker Others
    trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) is a geometric isomer of Cisplatin (HY-17394). Trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage while exhibiting low cytotoxicity. Trans-Platinum(II)diammine dichloride is useful for studying DNA-protein cross-links .
    trans-Platinum(II)diammine dichloride
  • HY-W034990
    Pt(acac)2

    platinum(II) acetylacetonate

    		 Others Others
    Pt (acac)2 (Platinum (II) acetylacetonate) is a halide-free platinum (II) acetylacetonate complex. Pt (acac)2 serves as a platinum source and precursor for the preparation of nanocatalysts and thin films, and also acts as a catalyst in N-allylation reactions .
    Pt(acac)2
  • HY-139813
    Phenanthriplatin

    		DNA Alkylator/Crosslinker Cancer
    Phenanthriplatin is a monovalent platinum(II)-based complex with a large cytotoxicity against cancer cells .
    Phenanthriplatin
  • HY-W414604
    Dichloro(1,2-diaminocyclohexane)platinum(II)

    		Biochemical Assay Reagents Cancer
    Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers .
    Dichloro(1,2-diaminocyclohexane)platinum(II)
  • HY-126060
    9-Ethylguanine

    		Nucleoside Antimetabolite/Analog Cancer
    9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .
    9-Ethylguanine
  • HY-W556802
    5-Oxodecanoic acid

    		Biochemical Assay Reagents Others
    Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers .
    5-Oxodecanoic acid
  • HY-W075885R
    trans-Platinum(II)diammine dichloride (Standard)

    trans-platinumdiamminedichloride (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) (Standard) is an analytical standard for trans-Platinum(II)diammine dichloride (HY-W075885). This product is intended for research and analytical applications. trans-Platinum(II)diammine dichloride is a geometric isomer of Cisplatin (HY-17394). trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage but exhibits low cytotoxicity. trans-Platinum(II)diammine dichloride can be used to study DNA-protein cross-links.
    trans-Platinum(II)diammine dichloride (Standard)
  • HY-175048
    Pt(II)-NHC complex 2C

    platinum(II)-N-heterocyclic carbene complex 2C

    		 Reactive Oxygen Species (ROS) Apoptosis ER-phagy Cancer
    Pt(II)-NHC Complex 2C (Platinum(II)-N-Heterocyclic Carbene complex 2C) (Compound 2C) is a platinum(II) complex based on N-heterocyclic carbene (NHC). Pt(II)-NHC Complex 2C is an immunogenic cell death (ICD) inducer that can induce endoplasmic reticulum stress (ERS) in liver cancer cells and produce reactive oxygen species (ROS), ultimately leading to the release of damage-associated molecular patterns (DAMP). Pt(II)-NHC Complex 2C blocks the cell cycle at the S phase and significantly induces cell apoptosis. Pt(II)-NHC Complex 2C shows anti-liver cancer potential in mouse models and activates immune cells in liver injury models.
    Pt(II)-NHC complex 2C
  • HY-155278
    Anticancer agent 162

    		Others Cancer
    Anticancer agent 162 (compound 1d) is an effective anticancer agent. Anticancer agent 162 induces oncosis of Hela cells with lipophilicity and cytotoxicity selectivity .
    Anticancer agent 162
  • HY-N16122
    Isopentylglycine

    		Drug Intermediate Cancer
    Isopentylglycine is an amino acid ligand that can be used to prepare metal complexes, such as palladium(II) complexes and platinum(II) complexes. Isopentylglycine can be used in cancer research .
    Isopentylglycine

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