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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
platinum(II)
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "platinum(II)" in MCE Product Catalog:
5
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Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. Lobaplatin can be used for research of cancer .
Cat. No.: HY-W075885
CAS No.: 14913-33-8
Synonyms: trans-platinumdiamminedichloride
Cat. No.: HY-W034990
CAS No.: 15170-57-7
Synonyms: platinum(II) acetylacetonate
Pt (acac)2 (Platinum (II) acetylacetonate) is a halide-free platinum (II) acetylacetonate complex. Pt (acac)2 serves as a platinum source and precursor for the preparation of nanocatalysts and thin films, and also acts as a catalyst in N-allylation reactions .
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Phenanthriplatin is a monovalent platinum(II)-based complex with a large cytotoxicity against cancer cells .
Cat. No.: HY-W414604
CAS No.: 52691-24-4
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Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers .
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9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .
Cat. No.: HY-W004588
CAS No.: 72914-19-3
tBu2bpy is a bidentate nitrogen ligand that coordinates with Pt (II) and Pt (IV) to form functional complexes. The tBu2bpy Pt (II) bis-crown ether complex selectively recognizes Mg 2+ and Zn 2+; both ions significantly enhance the fluorescence of the complex and cause a blue shift of the absorption peak. Its six-coordinate Pt (IV) complex [Pt (X)2Me2 ( tBu2bpy)] inhibits the proliferation of tumor cells. tBu2bpy Pt (IV) complexes bind to DNA through multiple interactions including partial intercalation, groove binding, and electrostatic interaction, and can competitively displace ethidium bromide and covalently bind to purine nucleotides. tBu2bpy can be used in relevant research in fields such as organic synthesis .
Cat. No.: HY-W556802
CAS No.: 624-01-1
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Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers .
Cat. No.: HY-W075885R
CAS No.: 14913-33-8
Synonyms: trans-platinumdiamminedichloride (Standard)
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trans-Platinum(II)diammine dichloride (trans-platinumdiamminedichloride) (Standard) is an analytical standard for trans-Platinum(II)diammine dichloride (HY-W075885). This product is intended for research and analytical applications. trans-Platinum(II)diammine dichloride is a geometric isomer of Cisplatin (HY-17394). trans-Platinum(II)diammine dichloride is a DNA cross-linking agent that induces significant DNA cross-link damage but exhibits low cytotoxicity. trans-Platinum(II)diammine dichloride can be used to study DNA-protein cross-links.
Cat. No.: HY-175048
CAS No.: 3035433-94-1
Synonyms: platinum(II)-N-heterocyclic carbene complex 2C
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Pt(II)-NHC Complex 2C (Platinum(II)-N-Heterocyclic Carbene complex 2C) (Compound 2C) is a platinum(II) complex based on N-heterocyclic carbene (NHC). Pt(II)-NHC Complex 2C is an immunogenic cell death (ICD) inducer that can induce endoplasmic reticulum stress (ERS) in liver cancer cells and produce reactive oxygen species (ROS), ultimately leading to the release of damage-associated molecular patterns (DAMP). Pt(II)-NHC Complex 2C blocks the cell cycle at the S phase and significantly induces cell apoptosis. Pt(II)-NHC Complex 2C shows anti-liver cancer potential in mouse models and activates immune cells in liver injury models.
Cat. No.: HY-155278
CAS No.: 2761736-66-5
Anticancer agent 162 (compound 1d) is an effective anticancer agent. Anticancer agent 162 induces oncosis of Hela cells with lipophilicity and cytotoxicity selectivity .
Cat. No.: HY-N16122
CAS No.: 23590-18-3
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Isopentylglycine is an amino acid ligand that can be used to prepare metal complexes, such as palladium(II) complexes and platinum(II) complexes. Isopentylglycine can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
