2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease Apoptosis Autophagy
  3. Reactive Oxygen Species (ROS) Apoptosis ER-phagy
  4. Pt(II)-NHC complex 2C

Pt(II)-NHC complex 2C  (Synonyms: Platinum(II)-N-heterocyclic carbene complex 2C)

Cat. No.: HY-175048
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Pt(II)-NHC Complex 2C (Platinum(II)-N-Heterocyclic Carbene complex 2C) (Compound 2C) is a platinum(II) complex based on N-heterocyclic carbene (NHC). Pt(II)-NHC Complex 2C is an immunogenic cell death (ICD) inducer that can induce endoplasmic reticulum stress (ERS) in liver cancer cells and produce reactive oxygen species (ROS), ultimately leading to the release of damage-associated molecular patterns (DAMP). Pt(II)-NHC Complex 2C blocks the cell cycle at the S phase and significantly induces cell apoptosis. Pt(II)-NHC Complex 2C shows anti-liver cancer potential in mouse models and activates immune cells in liver injury models.

For research use only. We do not sell to patients.

Pt(II)-NHC complex 2C

Pt(II)-NHC complex 2C Chemical Structure

CAS No. : 3035433-94-1

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Pt(II)-NHC complex 2C Related Antibodies

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Description

Pt(II)-NHC Complex 2C (Platinum(II)-N-Heterocyclic Carbene complex 2C) (Compound 2C) is a platinum(II) complex based on N-heterocyclic carbene (NHC). Pt(II)-NHC Complex 2C is an immunogenic cell death (ICD) inducer that can induce endoplasmic reticulum stress (ERS) in liver cancer cells and produce reactive oxygen species (ROS), ultimately leading to the release of damage-associated molecular patterns (DAMP). Pt(II)-NHC Complex 2C blocks the cell cycle at the S phase and significantly induces cell apoptosis. Pt(II)-NHC Complex 2C shows anti-liver cancer potential in mouse models and activates immune cells in liver injury models.

Molecular Weight

840.35

Formula

C24H23F2I2N3Pt
CAS No.
SMILES

I[Pt](I)([N]1=CC=CC=C1)=C(N2CC)N(CC)C(C3=CC=C(F)C=C3)=C2C4=CC=C(F)C=C4
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Room temperature in continental US; may vary elsewhere.
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Pt(II)-NHC complex 2C Related Classifications

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Keywords:

Pt(II)-NHC complex 2C3035433-94-1Platinum(II)-N-heterocyclic carbene complex 2CReactive Oxygen Species (ROS)ApoptosisER-phagyEndoplasmic reticulum autophagyPt(II)-N-heterocyclic carbene (Pt-NHC)immunogenic cell death (ICD)hepatocellular carcinoma (HCC)reactive oxygen species (ROS)Inhibitorinhibitorinhibit

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