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porphyrin derivatives

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By Targets:	Apoptosis (1) Endogenous Metabolite (3) Fluorescent Dye (1) Isotope-Labeled Compounds (1) MOFs (3) Pyroptosis (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) STAT (1) Topoisomerase (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (1)

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Isotope-Labeled Compounds

Targets Recommended: Amino Acid Derivatives

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101398

Coproporphyrin III 2 Publications Verification Zincphyrin	MOFs Endogenous Metabolite	Others
Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .

HY-W073080

Coproporphyrin I dihydrochloride	MOFs	Others
Coproporphyrin I dihydrochlorideIt is an organic compound belonging to the class of porphyrins. It is a derivative of heme, an iron-containing molecule found in hemoglobin and other proteins. Coproporphyrin I dihydrochlorideOften used as a biomarker in the assessment of certain liver and metabolic diseases, especially those related to bile synthesis and transport. It can also be used as a reference standard for analytical chemistry and pharmacological research.

HY-103656

Tetraphenylporphyrin TPP; Tetraphenylporphine; meso-Tetraphenylporphyrin	MOFs	Cancer
Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .

HY-W035136

Meso-tetrakis(4-aminophenyl)porphyrin	Endogenous Metabolite	Others
Meso-tetrakis(4-aminophenyl)porphyrin (IV) is a porphyrin derivative .

HY-W714691

Coproporphyrin III-15N4 Zincphyrin-¹⁵N₄	Isotope-Labeled Compounds Endogenous Metabolite	Others
Coproporphyrin III- ¹⁵N₄ (Zincphyrin- ¹⁵N₄) is the ¹⁵N-labeled Coproporphyrin III (HY-101398). Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .

HY-W008874

meso-Tetra(4-pyridyl)porphine	Topoisomerase	Cancer
meso-Tetra(4-pyridyl)porphine (Compound 10) is a porphyrin derivative. meso-Tetra(4-pyridyl)porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC₅₀ value greater than 50 µM. meso-Tetra(4-pyridyl)porphine can be used in tumor research .

HY-116525

Octaethylporphyrin	Reactive Oxygen Species (ROS)	Cancer
Octaethylporphyrin is a porphyrin derivative. Octaethylporphyrin is a photodynamic therapy (PDT) agent .

HY-P10656

Ac-DEVDD-TPP	Apoptosis Pyroptosis	Cancer
Ac-DEVDD-TPP is a porphyrin derivative that can be converted into D-TPP by caspase-3 cleavage and laser irradiation. The formed porphyrin nanofibers can effectively induce Apoptosis and Pyroptosis. Ac-DEVDD-TPP has antitumor activity .

HY-159157

Anti-inflammatory agent 92	STAT	Inflammation/Immunology
Anti-inflammatory agent 92 (compound LD4) is a porphyrin derivative. Anti-inflammatory agent 92 has anti-inflammatory properties. Anti-inflammatory agent 92 can alleviate ulcerative colitis by inhibiting the STAT3-EPHX2 axis .

HY-176913

TA	Fluorescent Dye	Others
TA is an anthracene derivative with ultrasound-activated luminescence properties. TA can be activated by ultrasound and emit fluorescence. TA is generally not used directly but can be used to construct TA-NP nanoparticles. The ultrasound-activated luminescence of TA-NPs is mainly concentrated in the wavelength range of 600~650 nm, exhibiting good penetration ability into biological tissues, making it suitable for in vivo imaging .

HY-103656R

Tetraphenylporphyrin (Standard) TPP (Standard); Tetraphenylporphine (Standard); meso-Tetraphenylporphyrin (Standard)	Reference Standards Others	Cancer
Tetraphenylporphyrin (Standard) is the analytical standard of Tetraphenylporphyrin (HY-103656). This product is intended for research and analytical applications. Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .

Cat. No.	Product Name	Type

HY-W073080

Coproporphyrin I dihydrochloride	Biochemical Assay Reagents
Coproporphyrin I dihydrochlorideIt is an organic compound belonging to the class of porphyrins. It is a derivative of heme, an iron-containing molecule found in hemoglobin and other proteins. Coproporphyrin I dihydrochlorideOften used as a biomarker in the assessment of certain liver and metabolic diseases, especially those related to bile synthesis and transport. It can also be used as a reference standard for analytical chemistry and pharmacological research.

Coproporphyrin I dihydrochloride

Biochemical Assay Reagents

Coproporphyrin I dihydrochlorideIt is an organic compound belonging to the class of porphyrins. It is a derivative of heme, an iron-containing molecule found in hemoglobin and other proteins. Coproporphyrin I dihydrochlorideOften used as a biomarker in the assessment of certain liver and metabolic diseases, especially those related to bile synthesis and transport. It can also be used as a reference standard for analytical chemistry and pharmacological research.

Cat. No.	Product Name	Target	Research Area

HY-P10656

Ac-DEVDD-TPP	Apoptosis Pyroptosis	Cancer
Ac-DEVDD-TPP is a porphyrin derivative that can be converted into D-TPP by caspase-3 cleavage and laser irradiation. The formed porphyrin nanofibers can effectively induce Apoptosis and Pyroptosis. Ac-DEVDD-TPP has antitumor activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101398

Coproporphyrin III 2 Publications Verification Zincphyrin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields Source Classification	MOFs Endogenous Metabolite
Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .

Cat. No.	Product Name	Chemical Structure

HY-W714691

Coproporphyrin III-15N4
Coproporphyrin III- ¹⁵N₄ (Zincphyrin- ¹⁵N₄) is the ¹⁵N-labeled Coproporphyrin III (HY-101398). Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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porphyrin derivatives

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products