TA
TA is an anthracene derivative with ultrasound-activated luminescence properties. TA can be activated by ultrasound and emit fluorescence. TA is generally not used directly but can be used to construct TA-NP nanoparticles. The ultrasound-activated luminescence of TA-NPs is mainly concentrated in the wavelength range of 600~650 nm, exhibiting good penetration ability into biological tissues, making it suitable for in vivo imaging.
For research use only. We do not sell to patients.
- CAS No.: 2470357-88-9
- Formula: C72H78O8
- Molecular Weight:1071.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2470357-88-9
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Molecular Weight 1071.38
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Formula C72H78O8
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SMILES
CCCCOC(C(OC)=C(C1=C23)C4=CC=CC=C4C(C5=C(C)C=C(C)C=C5C)=C1C(OC)=C(OCCCC)C3=C(C6=C78)C(OCCCC)=C(OC)C7=C9C=CC=CC9=C(C%10=C(C)C=C(C)C=C%10C)C8=C%11OC)=C2C6=C%11OCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Bioluminescent/Fluorescent Imaging Xenograft
Bioluminescent and fluorescent imaging xenograft models use tumor cells engineered to express optical reporters so tumor engraftment, growth, dissemination, and treatment response can be monitored longitudinally in living animals and validated ex vivo. Bioluminescence imaging usually measures luciferase activity after substrate administration and is commonly used as a surrogate for viable reporter-expressing tumor burden, while fluorescence imaging measures reporter or probe emission and can support tumor localization, ex vivo confirmation, or complementary multimodal analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)