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prostaglandin H2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Prostaglandin Receptor (13) Adrenergic Receptor (1) Amyloid-β (1) COX (1) Drug Isomer (1) Endogenous Metabolite (2) Fluorescent Dye (2) Leukotriene Receptor (1) Reference Standards (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (8) Endocrinology (6) Inflammation/Immunology (5) Neurological Disease (4)

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Targets Recommended: Prostaglandin Receptor PGE synthase

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-136500

Prostaglandin H2 PGH2	Endogenous Metabolite Amyloid-β	Neurological Disease Inflammation/Immunology
Prostaglandin H2 (PGH2) is an endothelium-derived contracting factor. Prostaglandin H2 can cause vasoconstriction. Prostaglandin H2 is the common precursor of all PGs and is produced by several cells that express cyclooxygen-ases. Prostaglandin H2 can activate PGD2 receptors CRTH2 and DP via interacting directly with the receptors and/or by giving rise to PGD2 after catalytic conversion by plasma proteins. Prostaglandin H2 can induce eosinophils migration and inhibit platelet aggregation. Prostaglandin H2 can accelerate the formation of dimers and higher oligomers of amyloid β_1-42. Prostaglandin H2 can be used for the researches of inflammation and neurological disease, such as Alzheimer disease .

HY-121825

U-44069	Prostaglandin Receptor	Cardiovascular Disease
U-44069 is a stable prostaglandin (PG) H2 analogue and a potent vasoconstrictor. U-44069 induces Ca influx at preglomerular vessels .

HY-105218A

Ifetroban sodium 1 Publications Verification BMS-180291 sodium	Prostaglandin Receptor	Cardiovascular Disease Endocrinology Cancer
Ifetroban (BMS-180291) sodium is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban sodium shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban sodium can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .

HY-105218

Ifetroban 1 Publications Verification BMS-180291	Prostaglandin Receptor	Cardiovascular Disease Endocrinology Cancer
Ifetroban (BMS-180291) is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .

HY-N10225

Thielavin A	Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration .

HY-113330

12S-HHT 1 Publications Verification 12(S)-HHTrE	Leukotriene Receptor Endogenous Metabolite	Inflammation/Immunology
12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H₂ (PGH₂) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity .

HY-P4406

*Abz-AGLA-Nba* 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4406A

*Abz-AGLA-Nba TFA*	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-176021

U-44069 serinol amide	Prostaglandin Receptor	Cardiovascular Disease
U-44069 serinol amide is a derivative of U-44069 (HY-121825). U-44069 serinol amide is a stable analog of the endoperoxide prostaglandin H2 (HY-136500). U-44069 serinol amide is a vasoconstrictor that can induce preglomerular Ca ²⁺ influx .

HY-168766

O-Acetylsalicylhydroxamic acid	Prostaglandin Receptor COX	Inflammation/Immunology
O-Acetylsalicylhydroxamic acid is an acetylation inhibitor of prostaglandin H2 synthase that can suppress PGE2 synthesis in the body and block the cyclooxygenase activity of PGHS in vitro. O-Acetylsalicylhydroxamic acid requires the presence of the active site residue Ser-529 to act on human PGHS-1; the S529A mutant is resistant to the inactivation effects of this inhibitor .

HY-101700A

LCB 2853 sodium	Prostaglandin Receptor	Cardiovascular Disease
LCB 2853 sodium is a potent *thromboxane A2/prostaglandin* H2 (TXA2/PGH2**) receptor antagonist. LCB 2853 sodium exhibits anti-aggregant and anti-vasospastic effects. LCB 2853 sodium can be used for the research of cardiovascular disease, such as hypertension .

HY-137483

Prostaglandin D2 serinol amide	Prostaglandin Receptor	Endocrinology
Prostaglandin D2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol .

HY-118556

Prostaglandin E2 serinol amide	Prostaglandin Receptor	Endocrinology
Prostaglandin E2 serinol amide is a weak inhibitor of the hydrolysis of [3H]2-oleoylglycerol. Prostaglandin E2 serinol amide is non-hydrolyzable to produce PGE2 and thus cannot inhibit leukotriene B4 biosynthesis, superoxide production, migration and antimicrobial peptide release .

HY-108282

(S)-Trimetoquinol hydrochloride (S)-AQL 208 hydrochloride; (S)-TMQ hydrochloride	Drug Isomer Adrenergic Receptor Prostaglandin Receptor	Cardiovascular Disease Neurological Disease
(S)-Trimetoquinol hydrochloride (Compound 1) is a apotent, nonselective, nonclassical β-adrenergic agonist and nonprostanoid *thromboxane A2/prostaglandin* H2** antagonist. (S)-Trimetoquinol hydrochloride can be used for research of neurological and cardiovascular disease .

HY-W009706A

Alclofenac sodium Allopydin sodium; W-7320 sodium	Prostaglandin Receptor	Neurological Disease Inflammation/Immunology
Alclofenac (Allopydin) sodium is an orally active prostaglandin synthase inhibitor with anti-inflammatory, analgesic and antipyretic activities. Alclofenac sodium irreversibly inhibits platelet aggregation. Alclofenac can be used in research related to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain and sciatica .

HY-W009706B

Alclofenac (lysinate) Allopydin (lysinate); W-7320 (lysinate)	Prostaglandin Receptor	Neurological Disease Inflammation/Immunology
Alclofenac (Allopydin) lysinate is an orally active prostaglandin synthase inhibitor with anti-inflammatory, analgesic and antipyretic activities. Alclofenac lysinate irreversibly inhibits platelet aggregation. Alclofenac lysinate can be used in research related to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain and sciatica .

HY-105218AR

Ifetroban sodium (Standard) BMS-180291 sodium (Standard)	Reference Standards Prostaglandin Receptor	Cardiovascular Disease Endocrinology Cancer
Ifetroban sodium (Standard) is the analytical standard of Ifetroban sodium (HY-105218A). This product is intended for research and analytical applications. Ifetroban (BMS-180291) sodium is an orally active antagonist of thromboxane A2 (TXA2) or prostaglandin H2 (PGH2) receptor. Ifetroban sodium shows antiplatelet activity, and inhibits tumor cell migration without affecting cell proliferation. Ifetroban sodium can be used for myocardial ischemia, hypertension, stroke, thrombosis, cardiomyopathy research .

Cat. No.	Nombre del producto	Target	Research Area

HY-P4406

*Abz-AGLA-Nba* 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-P4406A

*Abz-AGLA-Nba TFA*	Fluorescent Dye	Others
Abz-AGLA-Nba TFA is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba TFA is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

Thielavin A	Cardiovascular Disease Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Source Classification	Prostaglandin Receptor
Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration .

12S-HHT 1 Publications Verification 12(S)-HHTrE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Leukotriene Receptor Endogenous Metabolite
12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H₂ (PGH₂) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity .

Species:	Human (3) Mouse (1) Rat (1)
Tag:	His (3) Tag Free (1)
Source:	HEK293 (4) E. coli (1)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P71036

	HPGDS Protein, Human Glutathione-Dependent PGD Synthase; Glutathione-Requiring prostaglandin D Synthase; prostaglandin-H2 D-Isomerase; HPGDS; GSTS; PGDS; PTGDS2	Human	E. coli
	HPGDS protein is a multifunctional enzyme with bifunctionality, and its C-terminal and N-terminal domains have different activities.The C terminus acts as an epoxide hydrolase, promoting xenobiotic metabolism by degrading harmful epoxides and regulating physiological mediator levels.HPGDS Protein, Human is the recombinant human-derived HPGDS protein, expressed by E.coli , with tag free.

HY-P71242A

	PTGDS Protein, Human (HEK293, His) prostaglandin-H2 D-Isomerase; Beta-Trace Protein; Cerebrin-28; Glutathione-Independent PGD Synthase; Lipocalin-Type prostaglandin-D Synthase; prostaglandin-D2 Synthase; PGD2 Synthase; PGDS; PGDS2; PTGDS; PDS	Human	HEK293
	The PTGDS protein catalyzes the conversion of PGH2 to PGD2, a prostaglandin that affects smooth muscle activity and platelet aggregation. It plays a role in central nervous system functions such as sedation, sleep, and allodynia. PTGDS Protein, Human (HEK293, His) is the recombinant human-derived PTGDS protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P71242

	PTGDS Protein, Human (HEK293, His, solution) prostaglandin-H2 D-Isomerase; Beta-Trace Protein; Cerebrin-28; Glutathione-Independent PGD Synthase; Lipocalin-Type prostaglandin-D Synthase; prostaglandin-D2 Synthase; PGD2 Synthase; PGDS; PGDS2; PTGDS; PDS	Human	HEK293
	The PTGDS protein catalyzes the conversion of PGH2 to PGD2, a prostaglandin that affects smooth muscle activity and platelet aggregation. It plays a role in central nervous system functions such as sedation, sleep, and allodynia. PTGDS Protein, Human (HEK293, His, solution) is the recombinant human-derived PTGDS protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73709

	PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Rat	HEK293
	The PGD2 synthase/PTGDS protein converts PGH2 to PGD2, which regulates smooth muscle and inhibits platelet aggregation.It affects central nervous system functions including sedation, NREM sleep, and potential anti-apoptotic effects on oligodendrocytes.PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) is the recombinant rat-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His, C-6*His labeled tag.

HY-P73710

	PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Mouse	HEK293
	PGD2 Synthase/PTGDS Protein, an enzyme, is involved in the synthesis of prostaglandin D2 (PGD2). Dysregulation of PGD2 Synthase/PTGDS Protein has been linked to allergic diseases and inflammation. Targeting PGD2 Synthase/PTGDS Protein may provide potential therapeutic interventions in these conditions by modulating PGD2 levels, reducing allergic responses, and managing inflammation-related disorders. PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) is the recombinant mouse-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His labeled tag.

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Host:	Mouse (1) Rabbit (5)
Reactivity:	Human (4) Rat (3) Mouse (5)
Application:	IHC-P (4) ICC/IF (6) IP (4) IHC-F (2) WB (6) ELISA (1)
Isotype:	IgG (5) IgG2b (1)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (3)
Modification:	Unmodified (4)

Cat. No.	Compare	Nombre del producto	Application	Reactivity	Image

HY-P82796

	Cyclooxygenase 2 Antibody (YA2541) Cyclooxygenase-2; COX-2; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; PES-2; PHS II; prostaglandin H2 synthase 2	WB, ICC/IF, IP	Mouse
	Cyclooxygenase 2 Antibody (YA2541) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclooxygenase 2.

HY-P82796A

	Cyclooxygenase 2 Antibody (YA2541)(PBS only) Cyclooxygenase-2; COX-2; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; PES-2; PHS II; prostaglandin H2 synthase 2	WB, ICC/IF, IP	Mouse
	Cyclooxygenase 2 Antibody (YA2541) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclooxygenase 2.

HY-P82792

	Cyclooxygenase 1 Antibody (YA2537) PTGS1; COX1; prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; prostaglandin-endoperoxide synthase 1	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Cyclooxygenase 1 Antibody (YA2537) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclooxygenase 1.

HY-P82792A

	Cyclooxygenase 1 Antibody (YA2537)(PBS only) PTGS1; COX1; prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; prostaglandin-endoperoxide synthase 1	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Cyclooxygenase 1 Antibody (YA2537) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclooxygenase 1.

HY-P80091

	COX2 Antibody (YA493) 3 Publications Verification PTGS2; COX 2; COX2; COX-2; Cyclooxygenase; Cyclooxygenase2; Cyclooxygenase-2; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PGHS2; PHS 2; PHS II; PHS2 ; prostaglandin endoperoxide synthase 2; prostaglandin G/H synthase 2 precursor; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase 2; prostaglandin H2 synthase 2; TIS10II; PGH2_HUMAN.	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	COX2 Antibody (YA493) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to COX2.

HY-P85939

	COX2 Antibody (YA5631) COX 2; COX-2; COX2; Cyclooxygenase 2; Cyclooxygenase 2b; Cyclooxygenase; Cyclooxygenase-2; Cyclooxygenase2; fj02a10; Glucocorticoid-regulated inflammatory cyclooxygenase; Glucocorticoid-regulated inflammatory prostaglandin G/H synthase; GRIPGHS; hCox 2; Macrophage activation-associated marker protein P71/73; OTTHUMP00000033524; PES-2; PGG/HS; PGH synthase 2; PGH2_HUMAN; PGHS 2; PGHS-2; PGHS2; PHS 2; PHS II; PHS2; prostaglandin endoperoxide synthase 2; prostaglandin G/H synthase and cyclooxygenase; prostaglandin endoperoxide synthase 2; prostaglandin G/H synthase 2; prostaglandin G/H synthase 2 precursor; prostaglandin G/H synthase and cyclooxygenase; prostaglandin G/H synthase; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin G/H synthase and cyclooxygenase; prostaglandin-endoperoxide synthase 2; PTGS2; ptgs2a; TIS10; TIS10 protein; unp1239; wu:fj02a10	IHC-P, WB, ICC/IF, ELISA	Human
	COX2 Antibody (YA5631) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to COX2.

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prostaglandin H2

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