118 Results for "

succinimidyl ester

" in MedChemExpress (MCE) Product Catalog:
Products (118)

118 Results for "succinimidyl ester" in MCE Product Catalog:

119
119 Publications Verification
Cat. No.: HY-D0938
CAS No.: 150347-59-4
Synonyms: CFSE; 5(6)-Carboxyfluorescein diacetate succinimidyl ester; 5(6)-CFDA N-succinmidyl ester
CFDA-SE is a fluorescent dye that can penetrate the cell membrane. It can react with the free amine group in the cytoskeleton protein inside the cell, and finally form a protein complex with fluorescence. After entering the cell, CFDA-SE locates in the cell membrane, cytoplasm and nucleus, and the fluorescence staining is strongest in the nucleus . CFDA-SE dye can be uniformly inherited by the cells with cell division and proliferation, and its attenuation is proportional to the number of cell divisions. This phenomenon can be detected and analyzed by flow cytometry under the excitation light of 488 nm, and can be used to detect the proliferation of cells .
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45
45 Cited Publications
Cat. No.: HY-112847A
Purity:  ≥98.0%
Synonyms: Sulfo-N-succinimidyl oleate sodium
Target:  

Mitophagy

Research Areas:  

Inflammation/Immunology

Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect .
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45
45 Cited Publications
Cat. No.: HY-D0819
CAS No.: 146368-14-1
Synonyms: Cy5 NHS ester; Sulfo-Cyanine5 succinimidyl ester
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.
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45
45 Cited Publications
Cat. No.: HY-D0819A
CAS No.: 1497420-70-8
Synonyms: Cy5 NHS ester triethylamine salt; Sulfo-Cyanine5 succinimidyl ester triethylamine salt
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
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10 Cited Publications
Cat. No.: HY-D0056
CAS No.: 150206-05-6
5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell permeable dye (Ex=492 nm, Em=517 nm). 5-Carboxyfluorescein diacetate N-succinimidyl ester can label cells by covalently binding to intracellular molecules. 5-Carboxyfluorescein diacetate N-succinimidyl ester is used to track lymphocyte migration and proliferation .
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8
8 Cited Publications
Cat. No.: HY-D0824
CAS No.: 477908-53-5
Synonyms: Sulfo-Cyanine7 succinimidyl ester
CY7-SE is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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8
8 Cited Publications
Cat. No.: HY-D0824A
Synonyms: Sulfo-Cyanine7 succinimidyl ester triethylamine
CY7-SE triethylamine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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4 Cited Publications
Cat. No.: HY-15937
CAS No.: 117548-22-8
Synonyms: 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers
5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.
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3
3 Cited Publications
Cat. No.: HY-D0723
CAS No.: 246256-50-8
Synonyms: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
5(6)-TAMRA SE is a fluorescent dye that emits red fluorescence. 5(6)-TAMRA SE binds to oligonucleotides and is used in DNA sequencing. 5(6)-TAMRA SE can be used in cancer research (Ex/Em = 565/580 nm) .
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2 Cited Publications
Cat. No.: HY-D0048
CAS No.: 150810-68-7
Synonyms: 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).
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2
2 Cited Publications
Cat. No.: HY-119523
CAS No.: 23024-29-5
Purity:  ≥97.0%
Synonyms: DSSeb; Sebacic acid bis N-succinimidyl ester
Research Areas:  

Others

Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .
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1
1 Cited Publications
Cat. No.: HY-135233
CAS No.: 76931-93-6
Purity:  99.56%
Synonyms: SATA
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
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1 Cited Publications
Cat. No.: HY-D0049
CAS No.: 150810-69-8
Synonyms: 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
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1
1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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1 Cited Publications
Cat. No.: HY-128926
CAS No.: 341498-08-6
Purity:  97.65%
Synonyms: N-succinimidyl 4-(2-pyridyldithio) pentanoate
Target:  

ADC Linkers

Research Areas:  

Cancer

SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate .
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1 Cited Publications
Cat. No.: HY-D1050
CAS No.: 82321-04-8
Synonyms: 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.
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Cat. No.: HY-133527
CAS No.: 198139-51-4
Purity:  95.08%
Synonyms: Oregon green 488 succinimidyl ester
OG 488, SE (Oregon green 488 succinimidyl ester), a fluorescent pH indicator, has many applications in biochemistry and neurosciences .
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Cat. No.: HY-140698
CAS No.: 92451-01-9
Purity:  ≥95.0%
Synonyms: mPEG5000-SC; mPEG5000-succinimidyl ester
Research Areas:  

Cancer

m-PEG5000-NHS ester (mPEG5000-SC; mPEG5000-Succinimidyl ester) is a pegylation reagent that targets the primary amino groups of branched polyethyleneimine on gold nanoparticles. m-PEG1000-NHS ester covalently links its PEG moiety to target amino groups via amine-mediated coupling chemistry. m-PEG1000-NHS ester helps improve the biocompatibility of modified gold nanoparticles used as CT contrast agents and prolongs their blood circulation time.
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Cat. No.: HY-W011541
CAS No.: 39028-27-8
Synonyms: Iodoacetic acid N-hydroxysuccinimide ester; N-succinimidyl Iodoacetate
Target:  

ADC Linkers

Research Areas:  

Cancer

SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-D0826
CAS No.: 186205-33-4
Synonyms: Cyanine2 succinimidyl ester Iodide
Target:  

Fluorescent Dye

Research Areas:  

Others

Cy2-SE Iodide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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