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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
switch region
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "switch region" in MCE Product Catalog:
Cat. No.: HY-P99145A
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Cat. No.: HY-151523
Purity: 96.24%
KRas G12R inhibitor 1 is a covalent inhibitor targeting the common oncogenic mutant KRas G12R with selectivity for the mutant arginine. KRas G12R inhibitor 1 possesses an α,β-diketoamide and exploits strong nucleophilicity of the mutant cysteine and irreversibly binds in the Switch II region of KRas. KRas G12R inhibitor 1 can be researched for K-Ras (G12R)-driven cancer such as pancreatic ductal adenocarcinoma (PDAC) .
Cat. No.: HY-P990171
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Cat. No.: HY-P990172
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Cat. No.: HY-P990269
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Cat. No.: HY-122685
CAS No.: 116679-70-0
UC-773587 is a selective SOS1 catalytic activity inhibitor. UC-773587 binds to the catalytic site of Sos1 over HRas and ITSN (a RhoGEF) and inhibits nucleotide exchange with an IC50 value of 4.5 μM. UC-773587 mappes to the Ras switch II interaction region of the Sos1 catalytic site. UC-773587 can be used for the study of prostate cancer .
Cat. No.: HY-P990304A
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Cat. No.: HY-P990270
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Cat. No.: HY-P990304B
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Cat. No.: HY-P990304C
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Cat. No.: HY-N21879
CAS No.: 88192-99-8
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Cat. No.: HY-N21895
CAS No.: 96789-48-9
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Cat. No.: HY-186223
CAS No.: 897375-76-7
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Enzyme modulator-1 (example 205) is a potent enzyme modulator that modulates p38, bcr-ab1, and VEGFR. Enzyme modulator-1 can be used for the research of cancer, rheumatoid arthritis, retinopathies including diabetic retinal neuropathy and macular degeneration .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
