Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
703 Results for "
tumor necrosis factor
" in MedChemExpress (MCE) Product Catalog:
Products (703)
703 Results for "tumor necrosis factor" in MCE Product Catalog:
68
68 Publications Verification
Cat. No.: HY-P7058
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Human
Source:
E. coli
37
37 Cited Publications
Cat. No.: HY-P7090
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Mouse
Source:
E. coli
30
30 Cited Publications
Synonyms: TNF-α Antagonist III
Target:
Research Areas:
R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
19
Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .
17
17 Cited Publications
Cat. No.: HY-P7425
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; tumor necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor Kappa B Ligand; OPGL; tumor necrosis factor Ligand
Species:
Mouse
Source:
E. coli
10
10 Cited Publications
Synonyms: TIC10; ONC-201
Target:
Research Areas:
Dordaviprone (TIC10) is a potent, orally active, and stable tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) inducer which acts by inhibiting Akt and ERK, consequently activating Foxo3a and significantly inducing cell surface TRAIL. Dordaviprone can cross the blood-brain barrier .
10
10 Cited Publications
Cat. No.: HY-P7424
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; tumor necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor Kappa B Ligand; OPGL; tumor necrosis factor Ligand
Species:
Human
Source:
E. coli
10
10 Cited Publications
Cat. No.: HY-19975
CAS No.: 946387-07-1
Target:
Research Areas:
RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM) . RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells .
9
9 Cited Publications
Cat. No.: HY-P70697
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Rat
Source:
E. coli
8
8 Cited Publications
Cat. No.: HY-P70426A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Human
Source:
E. coli
8
7
7 Cited Publications
Cat. No.: HY-P7224
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic factor I; MDNCF; tumor necrosis factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-Cell Chemotactic factor; GCP-1; Interleukin 8; Monocyte-Derived Neutrophil Chemotactic factor; Interleukin-8; Monocyte-Derived Neutrophil-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine Subfamily B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; Neutrophil-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived Neutrophil Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived Neutrophil Activating Peptide
Species:
Human
Source:
E. coli
6
6 Cited Publications
Cat. No.: HY-P70800
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Rabbit
Source:
E. coli
6
6 Cited Publications
Cat. No.: HY-P73388
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; tumor necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor Kappa B Ligand; OPGL; tumor necrosis factor Ligand
Species:
Mouse
Source:
HEK293
5
4
4 Cited Publications
Target:
Research Areas:
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .
4
4 Cited Publications
Cat. No.: HY-P70571
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Mouse
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P7417
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNF; tumor necrosis factor (TNF Superfamily, Member 2); Prev. TNFA; tumor necrosis factor-Alpha; TNF-Alpha; tumor Necrotic factor Alpha; TNFSF2; TNF Superfamily, Member 2; tumor necrosis factor Ligand Superfamily Member 2; TNF, Macrophage-Derived; TNF-A;
Species:
Mouse
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P73386
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF11; tumor necrosis factor (Ligand) Superfamily, Member 11; TNF Superfamily Member 11; Receptor Activator Of Nuclear factor Kappa-B Ligand; TRANCE; TNLG6B; RANKL; Receptor Activator Of Nuclear factor Kappa B Ligand; OPGL; tumor necrosis factor Ligand
Species:
Human
Source:
HEK293
4
Target:
Research Areas:
CJ-42794 (CJ-042794) is a potent, orally active, selective prostaglandin E receptor 4 (EP4) antagonist with an IC50 value of 10 nM, which is 200-fold more selective than EP1, EP2 and EP3. CJ-42794 can be used in research of gastric ulcers .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
