Sodium phosphate dibasic heptahydrate
Based on 1 Customer Validation
Sodium phosphate dibasic heptahydrate is an orally active and osmotic laxative, often used as a component of over-the-counter gastrointestinal lavage drugs. Sodium phosphate dibasic heptahydrate draws water into the intestinal lumen, maintains electrical neutrality by retaining cations in the intestinal lumen, and thereby alters fecal volume, consistency and phosphate levels. Sodium phosphate dibasic heptahydrate can be used to generate self-assembled calcium phosphate tubular scaffolds, which support the adhesion, survival and elongation of mesenchymal stem cells. Sodium phosphate dibasic heptahydrate can be applied to research on factitious disorders and related fields.
For research use only. We do not sell to patients.
- Purity: 98.74%
- CAS No.: 7782-85-6
- Formula: Na2HPO4·7H2O
- Molecular Weight:268.07
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
Sodium phosphate dibasic heptahydrate (0.2-1 M; 4 weeks, 10-60 min, 48 h, 4 h) induces the self-assembly of calcium phosphate tubular scaffolds, where the 0.8 M concentration generates tubular structures with good repeatability and high occurrence frequency, which can support the adhesion and survival of sheep bone marrow-derived mesenchymal stem cells; compared with heat-treated β-tricalcium phosphate scaffolds, calcium-deficient hydroxyapatite scaffolds prepared from Sodium phosphate dibasic heptahydrate promote more extensive cell spreading[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7782-85-6
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Appearance Solid
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Molecular Weight 268.07
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Formula Na2HPO4·7H2O
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Color White to off-white
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SMILES
O=P(O[Na])(O[Na])O.O.O.O.O.O.O.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 100 mg/mL (373.04 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Fine KD, et al. Investigation and diagnosis of diarrhea caused by sodium phosphate. Dig Dis Sci. 1998;43(12):2708-2714. [Content Brief]
[2]. Lebiedzińska A, et al. High-Performance Liquid Chromatography Method for the Determination of Folic Acid in Fortified Food Products. Toxicol Mech Methods. 2008;18(6):463-467. [Content Brief]
[3]. Hughes EAB, et al. Chemobrionic structures in tissue engineering: self-assembling calcium phosphate tubes as cellular scaffolds. Biomater Sci. 2020;8(3):812-822. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.7304 mL | 18.6518 mL | 37.3037 mL | 93.2592 mL |
| 5 mM | 0.7461 mL | 3.7304 mL | 7.4607 mL | 18.6518 mL | |
| 10 mM | 0.3730 mL | 1.8652 mL | 3.7304 mL | 9.3259 mL | |
| 15 mM | 0.2487 mL | 1.2435 mL | 2.4869 mL | 6.2173 mL | |
| 20 mM | 0.1865 mL | 0.9326 mL | 1.8652 mL | 4.6630 mL | |
| 25 mM | 0.1492 mL | 0.7461 mL | 1.4921 mL | 3.7304 mL | |
| 30 mM | 0.1243 mL | 0.6217 mL | 1.2435 mL | 3.1086 mL | |
| 40 mM | 0.0933 mL | 0.4663 mL | 0.9326 mL | 2.3315 mL | |
| 50 mM | 0.0746 mL | 0.3730 mL | 0.7461 mL | 1.8652 mL | |
| 60 mM | 0.0622 mL | 0.3109 mL | 0.6217 mL | 1.5543 mL | |
| 80 mM | 0.0466 mL | 0.2331 mL | 0.4663 mL | 1.1657 mL | |
| 100 mM | 0.0373 mL | 0.1865 mL | 0.3730 mL | 0.9326 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
- Sodium phosphate dibasic heptahydrate
- 7782-85-6
- Biochemical Assay Reagents
- mesenchymal stem cell
- folic acid
- factitious disorders
- sheep bone marrow derived mesenchymal stem cells
- calcium phosphate tubular scaffolds
- calcium deficient hydroxyapatite scaffolds
- 5-formyltetrahydrofolate
- beta tricalcium phosphate scaffolds
- intestinal lumen
- gastrointestinal lavage
- Inhibitor
- inhibitor
- inhibit