Sp-ATPαS tetrasodium solution (100mM)
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Sp-ATPαS tetrasodium is a thiophosphonate analogue of ATP. Sp-ATPαS tetrasodium is a competitive antagonist of the human P2Y1 receptor and can inhibit the calcium signal induced by ADP. Sp-ATPαS tetrasodium has higher metabolic stability than ATP. Sp-ATPαS tetrasodium can be used to study the binding mode of metal-nucleotide in enzymatic reactions.
For research use only. We do not sell to patients.
- Purity: 98.60%
- Formula: C10H12N5Na4O12P3S
- Molecular Weight:611.17
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Storage:
Solution, -20°C, protect from light, 2 years
All P2Y Receptor Isoforms
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Biological Activity
Chemical Information
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Appearance Liquid
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Molecular Weight 611.17
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Formula C10H12N5Na4O12P3S
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Color Colorless to light yellow
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1CO[P@@](OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(S[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, protect from light, 2 years
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Connolly BA, Eckstein F. S-Methylated nucleoside phosphorothioates as probes of enzyme metal X nucleotide binding sites. Biochemistry. 1982 Nov 23;21(24):6158-67. [Content Brief]
[2]. Léon C, et al. The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells. FEBS Lett. 1997 Feb 10;403(1):26-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)