1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR TAM Receptor
  3. TAM&Met-IN-1

TAM&Met-IN-1 is a potent TAM and c-Met kinase inhibitor with IC50 values of 6.1 nM, 13.2 nM and 21.6 nM for AXL, MER and TYRO3, respectively. TAM&Met-IN-1 can be used for researching anticancer.

For research use only. We do not sell to patients.

TAM&Met-IN-1 Chemical Structure

TAM&Met-IN-1 Chemical Structure

CAS No. : 2412356-57-9

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Description

TAM&Met-IN-1 is a potent TAM and c-Met kinase inhibitor with IC50 values of 6.1 nM, 13.2 nM and 21.6 nM for AXL, MER and TYRO3, respectively. TAM&Met-IN-1 can be used for researching anticancer[1].

IC50 & Target

IC50: 6.1 nM (AXL), 13.2 nM (MER), 21.6 nM (TYRO3)[1]

Molecular Weight

591.57

Formula

C29H27F2N7O5

CAS No.
SMILES

OC[C@@H](C)NC1=NNC2=NC=CC(OC3=C(C=C(C=C3)NC(C(C(N4C5=CC=C(C=C5)F)=O)=CN(C(C)C)C4=O)=O)F)=C12

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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TAM&Met-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TAM&Met-IN-1
Cat. No.:
HY-147218
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