Thalidomide-O-PEG2-NHS ester
Based on 1 Customer Validation
Thalidomide-O-PEG2-NHS ester, is synthesized compound that incorporatess the Thalidomide based cereblon ligand and the PEG linker used in PROTAC technology.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 2639395-34-7
- Formula: C24H25N3O11
- Molecular Weight:531.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2639395-34-7
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Appearance Solid
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Molecular Weight 531.47
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Formula C24H25N3O11
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Color White to off-white
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SMILES
O=C(CCOCCOCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)ON4C(CCC4=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (94.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8816 mL | 9.4079 mL | 18.8157 mL | 47.0393 mL |
| 5 mM | 0.3763 mL | 1.8816 mL | 3.7631 mL | 9.4079 mL | |
| 10 mM | 0.1882 mL | 0.9408 mL | 1.8816 mL | 4.7039 mL | |
| 15 mM | 0.1254 mL | 0.6272 mL | 1.2544 mL | 3.1360 mL | |
| 20 mM | 0.0941 mL | 0.4704 mL | 0.9408 mL | 2.3520 mL | |
| 25 mM | 0.0753 mL | 0.3763 mL | 0.7526 mL | 1.8816 mL | |
| 30 mM | 0.0627 mL | 0.3136 mL | 0.6272 mL | 1.5680 mL | |
| 40 mM | 0.0470 mL | 0.2352 mL | 0.4704 mL | 1.1760 mL | |
| 50 mM | 0.0376 mL | 0.1882 mL | 0.3763 mL | 0.9408 mL | |
| 60 mM | 0.0314 mL | 0.1568 mL | 0.3136 mL | 0.7840 mL | |
| 80 mM | 0.0235 mL | 0.1176 mL | 0.2352 mL | 0.5880 mL |