2. PROTAC Antibody-drug Conjugate/ADC Related
  3. PROTAC Linkers ADC Linker
  4. THP-PEG6-OH

THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

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THP-PEG6-OH

THP-PEG6-OH 화학구조

CAS No. : 42607-87-4

사이즈 가격 재고 수량
100 mg 해외재고보유
250 mg 해외재고보유
1 g 해외재고보유
5 g   견적 받기  
10 g   견적 받기  

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THP-PEG6-OH Related Antibodies

Top Publications Citing Use of Products

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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC50 & Target

PEGs

 

Non-cleavable Linker

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

THP-PEG6-OH Related Antibodies
분자량

366.45

화학식

C17H34O8
CAS No.
Appearance

Liquid (Density: 1.10±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

OCCOCCOCCOCCOCCOCCOC1CCCCO1
선적

Room temperature in continental US; may vary elsewhere.
보관
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
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THP-PEG6-OH Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

THP-PEG6-OH42607-87-4PROTAC LinkersADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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상품명:
THP-PEG6-OH
Cat. No.:
HY-126918
수량:
MCE Japan Authorized Agent:

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