THR-β agonist 2
Based on 1 Customer Validation
THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3).
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 2440027-77-8
- Formula: C18H8Cl2N6O4
- Molecular Weight:443.20
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2440027-77-8
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Appearance Solid
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Molecular Weight 443.20
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Formula C18H8Cl2N6O4
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Color Off-white to light yellow
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SMILES
N#CC1=NN(C2=CC(Cl)=C(OC3=NNC(C4=C3C=CC=C4)=O)C(Cl)=C2)C(NC1=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 350 mg/mL (789.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2563 mL | 11.2816 mL | 22.5632 mL | 56.4079 mL |
| 5 mM | 0.4513 mL | 2.2563 mL | 4.5126 mL | 11.2816 mL | |
| 10 mM | 0.2256 mL | 1.1282 mL | 2.2563 mL | 5.6408 mL | |
| 15 mM | 0.1504 mL | 0.7521 mL | 1.5042 mL | 3.7605 mL | |
| 20 mM | 0.1128 mL | 0.5641 mL | 1.1282 mL | 2.8204 mL | |
| 25 mM | 0.0903 mL | 0.4513 mL | 0.9025 mL | 2.2563 mL | |
| 30 mM | 0.0752 mL | 0.3761 mL | 0.7521 mL | 1.8803 mL | |
| 40 mM | 0.0564 mL | 0.2820 mL | 0.5641 mL | 1.4102 mL | |
| 50 mM | 0.0451 mL | 0.2256 mL | 0.4513 mL | 1.1282 mL | |
| 60 mM | 0.0376 mL | 0.1880 mL | 0.3761 mL | 0.9401 mL | |
| 80 mM | 0.0282 mL | 0.1410 mL | 0.2820 mL | 0.7051 mL | |
| 100 mM | 0.0226 mL | 0.1128 mL | 0.2256 mL | 0.5641 mL |
THR-β agonist 2 Related Classifications
HY-143613 Related Classifications
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