trans-p-Sinapoyl-β-D-glucopyranoside
trans-p-Sinapoyl-β-D-glucopyranoside is a phenolic acid glycoside and Antibacterial agent. trans-p-Sinapoyl-β-D-glucopyranoside can be isolated from chili pepper (Capsicum annuum L.) and Sorbaria tomentosa. trans-p-Sinapoyl-β-D-glucopyranoside scavenges DPPH free radicals. trans-p-Sinapoyl-β-D-glucopyranoside exhibits anticancer, anti-inflammatory, antidiabetic and antihypertensive activities. trans-p-Sinapoyl-β-D-glucopyranoside exerts antioxidant activity by inhibiting the fading of β-Carotene (HY-N0411) emulsion.
For research use only. We do not sell to patients.
- CAS No.: 117405-52-4
- Formula: C17H22O10
- Molecular Weight:386.35
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>100 μM
Compound: 23
|
Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction
Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction
|
[PMID: 27623545] |
| BV-2 | IC50 |
100 μM
Compound: 23
|
Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction
Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction
|
[PMID: 27623545] |
| RAW264.7 | IC50 |
18.7 μM
Compound: 2
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production pretreated with compound for 2 hrs followed by LPS stimulation measured after 18 hrs by gGriess reagent based assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production pretreated with compound for 2 hrs followed by LPS stimulation measured after 18 hrs by gGriess reagent based assay
|
[PMID: 34658231] |
In Vitro
trans-p-Sinapoyl-β-D-glucopyranoside (1.2 × 10-3 mol/dm3; 3 h) exhibits antioxidant activity in the β-carotene-linoleic acid system, with an inhibition rate of 63.2%[3].
trans-p-Sinapoyl-β-D-glucopyranoside (1.2 × 10−5 mol/dm3; 30 min) exhibits free radical scavenging activity in the DPPH system, with a decolorization rate of 13.3%[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 117405-52-4
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Appearance Solid
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Molecular Weight 386.35
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Formula C17H22O10
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SMILES
COC(C=C(C=C1OC)/C=C/C(O)=O)=C1O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
[1]. Materska M, et al. Isolation and structure elucidation of flavonoid and phenolic acid glycosides from pericarp of hot pepper fruit Capsicum annuum L. Phytochemistry. 2003 Aug;63(8):893-8. [Content Brief]
[3]. Materska M, et al. Antioxidant activity of the main phenolic compounds isolated from hot pepper fruit (Capsicum annuum L). Journal of agricultural and food chemistry. 2005 Mar 09;53(5):1750-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- trans-p-Sinapoyl-β-D-glucopyranoside
- 117405-52-4
- Bacterial
- Reactive Oxygen Species (ROS)
- urinary bladder cancer
- DPPH free radical scavenging
- hepatocellular carcinoma
- sinapic acid
- β-carotene linoleic acid system
- β-carotene emulsion bleaching
- Capsicum annuum L.
- NMR
- Sorbaria tomentosa
- lung adenocarcinoma
- Inhibitor
- inhibitor
- inhibit