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Cat. No.: HY-W014325R

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TRPM8 agonist WS-3 (Standard)

(Synonyms: Framidice 3 (Standard))

TRPM8 agonist WS-3 (Standard) is the analytical standard of TRPM8 agonist WS-3. This product is intended for research and analytical applications. TRPM8 agonist WS-3 is an specific agonist of TRPM8 with an EC₅₀ of 3.7 μM. TRPM8 agonist WS-3 inhibits epileptic seizures through a TRPM8 dependent mechanism. TRPM8 agonist WS-3 can be used for research on epilepsy and other conditions.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 39711-79-0
Formula: C₁₃H₂₅NO
Molecular Weight:211.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TRPM8 agonist WS-3 (Standard) Chemical Structure

CAS No.: 39711-79-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 39711-79-0
Molecular Weight 211.35
Formula C₁₃H₂₅NO
SMILES

CC(C)C1CCC(C)CC1C(NCC)=O
Synonyms

Framidice 3 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Behrendt HJ, et al. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. [Content Brief]

[2]. Moriyama H, et al. Anti-seizure effects of WS-3, a TRPM8 agonist, on focal onset seizure mouse model via reduction of extracellular glutamate levels. Neuropsychopharmacology. 2025 Nov;50(12):1855-1863. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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