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Cat. No.: HY-50911R

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Turofexorate isopropyl (Standard)

Name: Turofexorate isopropyl (Standard)
Brand: MedChemExpress
SKU: HY-50911R
Price: 145.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: FXR-450 (Standard); XL335 (Standard); WAY-362450 (Standard))

Turofexorate isopropyl (Standard) is the analytical standard of Turofexorate isopropyl. This product is intended for research and analytical applications. Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 629664-81-9
Formula: C₂₅H₂₄F₂N₂O₃
Molecular Weight:438.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Turofexorate isopropyl (Standard) Chemical Structure

CAS No.: 629664-81-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 629664-81-9
Molecular Weight 438.47
Formula C₂₅H₂₄F₂N₂O₃
SMILES

O=C(C1=CN(C(C2=CC=C(F)C(F)=C2)=O)CC(C)(C)C3=C1NC4=C3C=CC=C4)OC(C)C
Synonyms

FXR-450 (Standard); XL335 (Standard); WAY-362450 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Flatt B, et al. Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR). J Med Chem. 2009 Feb 26;52(4):904-7. [Content Brief]

[2]. Evans MJ, et al. A synthetic farnesoid X receptor (FXR) agonist promotes cholesterol lowering in models of dyslipidemia. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G543-52. [Content Brief]

[3]. Hartman HB, et al. Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice. J Lipid Res. 2009 Jun;50(6):1090-100. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Turofexorate isopropyl (Standard)