(Z)-7-Tetradecen-2-one 

(Z)-7-Tetradecen-2-one acts as a species-specific nematicide. (Z)-7-Tetradecen-2-one induces terminal embryogenesis, morphological abnormalities, irreversible developmental arrest and increases eggshell permeability in *Pristionchus pacificus* embryos. (Z)-7-Tetradecen-2-one exerts olfactory attraction toward *Pristionchus pacificus*. (Z)-7-Tetradecen-2-one can be used to study the symbiotic relationship between hosts and nematodes^[1][2].

(Z)-7-tetradecen-2-one (0.5% volatile, 10 μL; 2-4 h) induces irreversible terminal embryonic development in 100% of early embryos of *Pristionchus pacificus* PS312. The minimum lethal exposure duration is 4 h for ex utero embryos at 0-4 h, and 3 h for ex utero embryos at 4-8 h, ultimately leading to abnormal embryonic morphology, partial tissue differentiation, and complete developmental arrest^[1].
(Z)-7-tetradecen-2-one (0.5% volatility; 4 h) increases eggshell permeability in embryos of *Pristionchus pacificus* PS312, PS1843 and RS5186. In sensitive strains, 65% to 90% of embryos exhibit FM4-64 staining of embryonic tissues after exposure, which correlates with irreversible developmental arrest^[1].
(Z)-7-tetradecen-2-one (0.5% volatile; 4 h) induces 100% irreversible developmental arrest in the circum-Pacific strain of *Pristionchus pacificus*, whereas 40%-60% developmental arrest occurs in the RS5278 and RS5419 strains, with no effect on *Caenorhabditis elegans* N2 embryos^[1].
(Z)-7-Tetradecen-2-one (0.1-10% dilution; 9-15 h) exhibits strong attractiveness to *Pristionchus pacificus*, while it shows repellent effects or no impact on other tested nematode species^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

210.36

C₁₄H₂₆O

146955-45-5

C(C/C=C\CCCCCC)CCC(C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Renahan T, et al. A species-specific nematocide that results in terminal embryogenesis. J Exp Biol. 2017;220(Pt 18):3238-3247.

  [2]. Herrmann M, et al. The nematode Pristionchus pacificus (Nematoda: Diplogastridae) is associated with the oriental beetle Exomala orientalis (Coleoptera: Scarabaeidae) in Japan. Zoolog Sci. 2007;24(9):883-889.