1-(2,3-Dichlorophenyl)ethanamine hydrochloride

Cat. No.: HY-107398: FAQs
Data Sheet Handling Instructions

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1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure.

For research use only. We do not sell to patients.

1-(2,3-Dichlorophenyl)ethanamine hydrochloride Chemical Structure

CAS No. : 39959-66-5

Size	Price	Stock	Quantity
1 mg	USD 47	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
References
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Description

In Vivo

1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats^[1]
Dosage:	50 mg/kg
Administration:	Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days
Result:	Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.

Molecular Weight

226.53

Formula

C₈H₁₀Cl₃N

CAS No.

39959-66-5

Appearance

Solid

Color

White to off-white

SMILES

CC(C1=C(C(Cl)=CC=C1)Cl)N.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (441.44 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4144 mL	22.0721 mL	44.1443 mL
5 mM	0.8829 mL	4.4144 mL	8.8289 mL
10 mM	0.4414 mL	2.2072 mL	4.4144 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Saavedra JM. Adrenaline levels in brain stem nuclei and effects of a PNMT inhibitor on spontaneously hypertensive rats. Brain Res. 1979 Apr 27;166(2):283-92. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.4144 mL	22.0721 mL	44.1443 mL	110.3607 mL
	5 mM	0.8829 mL	4.4144 mL	8.8289 mL	22.0721 mL
	10 mM	0.4414 mL	2.2072 mL	4.4144 mL	11.0361 mL
	15 mM	0.2943 mL	1.4715 mL	2.9430 mL	7.3574 mL
	20 mM	0.2207 mL	1.1036 mL	2.2072 mL	5.5180 mL
	25 mM	0.1766 mL	0.8829 mL	1.7658 mL	4.4144 mL
	30 mM	0.1471 mL	0.7357 mL	1.4715 mL	3.6787 mL
	40 mM	0.1104 mL	0.5518 mL	1.1036 mL	2.7590 mL
	50 mM	0.0883 mL	0.4414 mL	0.8829 mL	2.2072 mL
	60 mM	0.0736 mL	0.3679 mL	0.7357 mL	1.8393 mL
	80 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3795 mL
	100 mM	0.0441 mL	0.2207 mL	0.4414 mL	1.1036 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.