1-(2,3-Dichlorophenyl)ethanamine hydrochloride
Based on 1 Customer Validation
1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 39959-66-5
- Formula: C8H10Cl3N
- Molecular Weight:226.53
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Adrenergic Receptor Isoforms
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats[1]
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Dosage:50 mg/kg
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Administration:Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days
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Result:Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.
Chemical Information
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CAS No. 39959-66-5
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Appearance Solid
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Molecular Weight 226.53
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Formula C8H10Cl3N
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Color White to off-white
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SMILES
CC(C1=C(C(Cl)=CC=C1)Cl)N.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (441.44 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.4144 mL | 22.0721 mL | 44.1443 mL | 110.3607 mL |
| 5 mM | 0.8829 mL | 4.4144 mL | 8.8289 mL | 22.0721 mL | |
| 10 mM | 0.4414 mL | 2.2072 mL | 4.4144 mL | 11.0361 mL | |
| 15 mM | 0.2943 mL | 1.4715 mL | 2.9430 mL | 7.3574 mL | |
| 20 mM | 0.2207 mL | 1.1036 mL | 2.2072 mL | 5.5180 mL | |
| 25 mM | 0.1766 mL | 0.8829 mL | 1.7658 mL | 4.4144 mL | |
| 30 mM | 0.1471 mL | 0.7357 mL | 1.4715 mL | 3.6787 mL | |
| 40 mM | 0.1104 mL | 0.5518 mL | 1.1036 mL | 2.7590 mL | |
| 50 mM | 0.0883 mL | 0.4414 mL | 0.8829 mL | 2.2072 mL | |
| 60 mM | 0.0736 mL | 0.3679 mL | 0.7357 mL | 1.8393 mL | |
| 80 mM | 0.0552 mL | 0.2759 mL | 0.5518 mL | 1.3795 mL | |
| 100 mM | 0.0441 mL | 0.2207 mL | 0.4414 mL | 1.1036 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.