1,2-Didehydrotanshinone IIA
1,2-Didehydrotanshinone IIA is a moderate AChE and BChE inhibitor, with an IC50 value of 5.98 μM for BChE. 1,2-Didehydrotanshinone IIA is a IDO inhibitor, with an IC50 value of 4.68 µM μM.
For research use only. We do not sell to patients.
- CAS No.: 119963-50-7
- Formula: C19H16O3
- Molecular Weight:292.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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BChE 5.98 μM (IC50) |
IDO 4.68 μM (IC50) |
Chemical Information
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CAS No. 119963-50-7
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Molecular Weight 292.33
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Formula C19H16O3
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SMILES
O=C1C(C2=C(C3=C1C(C=CCC4(C)C)=C4C=C3)OC=C2C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. F Sezer Senol, et al. Selective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L. Phytochemistry. 2017 Jan:133:33-44. [Content Brief]
[2]. Zhang H, Liu W, Liu Z, et al. Discovery of indoleamine 2,3-dioxygenase inhibitors using machine learning based virtual screening. Medchemcomm. 2018;9(6):937-945. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)