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Cat. No.: HY-137158

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16-Phenoxy tetranor Prostaglandin E2

(Synonyms: 16-Phenoxy tetranor PGE2)

16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.1 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.

For research use only. We do not sell to patients.

CAS No.: 54382-74-0
Formula: C₂₂H₂₈O₆
Molecular Weight:388.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

16-Phenoxy tetranor Prostaglandin E2 Chemical Structure

CAS No.: 54382-74-0

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

All Prostaglandin Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	0.89 nM Compound: 4	Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay	[PMID: 28105284]
CHO	EC₅₀	16 nM Compound: 4	Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay	[PMID: 28105284]

Chemical Information

CAS No. 54382-74-0
Molecular Weight 388.45
Formula C₂₂H₂₈O₆
SMILES

OC(CCC/C=C\C[C@@H](C(C1)=O)[C@H]([C@@H]1O)/C=C/[C@@H](O)COC2=CC=CC=C2)=O
Synonyms

16-Phenoxy tetranor PGE2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kuhnz, et al. Identification of the major metabolites of the prostaglandin E2-analogue sulprostone in human plasma, and isolation from urine (in vivo) and liver perfusate (in vitro) of female guinea-pigs. Drug Metab. Dispos. 19(5), 920-925 (1991).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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16-Phenoxy tetranor Prostaglandin E2

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16-Phenoxy tetranor Prostaglandin E2

High-Throughput Bioactive Compound Library

All Prostaglandin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

16-Phenoxy tetranor Prostaglandin E2 Related Classifications

HY-137158 Related Classifications