1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 3β-Isodihydrocadambine

3β-Isodihydrocadambine, a derivative of cadambine, is obtained from the bark and leaves of Neolamarckia cadamba and possesses notable antimalarial, antiproliferative, antioxidant, anticancer, and anti-inflammatory properties.

For research use only. We do not sell to patients.

3β-Isodihydrocadambine

3β-Isodihydrocadambine Chemical Structure

CAS No. : 62014-69-1

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Description

3β-Isodihydrocadambine, a derivative of cadambine, is obtained from the bark and leaves of Neolamarckia cadamba and possesses notable antimalarial, antiproliferative, antioxidant, anticancer, and anti-inflammatory properties.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 80 μM
Compound: 17
Cytotoxicity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 31804070]
HepG2 IC50
> 80 μM
Compound: 17
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 31804070]
MCF7 IC50
> 80 μM
Compound: 17
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
[PMID: 31804070]
Molecular Weight

546.57

Formula

C27H34N2O10

CAS No.
SMILES

OC[C@@H]1N2[C@@](C[C@@]3([H])[C@]1([H])[C@@H](OC=C3C(OC)=O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)([H])C5=C(CC2)C6=CC=CC=C6N5

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
3β-Isodihydrocadambine
Cat. No.:
HY-N12609
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