5-Aza-7-deazaguanine
Based on 1 publication(s) in Google Scholar
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 67410-64-4
- Formula: C5H5N5O
- Molecular Weight:151.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 5-Aza-7-deazaguanine
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Biological Activity
Purine nucleoside phosphorylase, Nucleoside Antimetabolite/Analog[1]
Chemical Information
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CAS No. 67410-64-4
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Appearance Solid
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Molecular Weight 151.13
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Formula C5H5N5O
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Color Off-white to light yellow
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SMILES
O=C1N=C(N)N=C2N1C=CN2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Theranostics
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3. [Abstract]2021 Jan 1;11(2):841-860. PMID: 33391508
Solvent & Solubility
H2O : 5 mg/mL (33.08 mM; ultrasonic and adjust pH to 9 with NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 6.6168 mL | 33.0841 mL | 66.1682 mL | 165.4205 mL |
| 5 mM | 1.3234 mL | 6.6168 mL | 13.2336 mL | 33.0841 mL | |
| 10 mM | 0.6617 mL | 3.3084 mL | 6.6168 mL | 16.5420 mL | |
| 15 mM | 0.4411 mL | 2.2056 mL | 4.4112 mL | 11.0280 mL | |
| 20 mM | 0.3308 mL | 1.6542 mL | 3.3084 mL | 8.2710 mL | |
| 25 mM | 0.2647 mL | 1.3234 mL | 2.6467 mL | 6.6168 mL | |
| 30 mM | 0.2206 mL | 1.1028 mL | 2.2056 mL | 5.5140 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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