5-HT2C agonist-12
5-HT2C agonist-12 (example.2) is a selective and orally active 5-HT2C receptor agonist. 5-HT2C agonist-12 can inhibit the accumulation of IP3 with an IC50 of 4.5 nM. 5-HT2C agonist-12 can induce a feeling of fullness, shorten the time of eating, and reduce calorie intake. 5-HT2C agonist-12 can be used for the research of obesity.
For research use only. We do not sell to patients.
- CAS No.: 616201-56-0
- Formula: C12H16ClNO
- Molecular Weight:225.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT2C Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
11 nM
Compound: 9b
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Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol release
Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol release
|
[PMID: 15713408] |
Chemical Information
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CAS No. 616201-56-0
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Molecular Weight 225.71
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Formula C12H16ClNO
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SMILES
ClC1=C(OC)C=C(CCNCC2C)C2=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)