5-Norbornene-2-methylamine
Based on 1 Customer Validation
5-Norbornene-2-methylamine (JBP) is a hydrophobic tag. 5-Norbornene-2-methylamine can be used for the synthesis of HyT degraders, such as PARP1 degrader-2 (HY-181460).
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 95-10-3
- Formula: C8H13N
- Molecular Weight:123.20
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Ubiquitination Compound Library
HY-L050
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E3 Ligase Ligand Library
HY-L128
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MCE Bioactive Compound Library
HY-L001V
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High-Throughput Bioactive Compound Library
HY-L205
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Amine Fragment Library
HY-L236
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3D Diverse Fragment Library
HY-L903
Biological Activity
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VHL |
5-Norbornene-2-methylamine (4 μM; 24 h) does not induce significant PARP1 degradation in MDA-MB-231 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MDA-MB-231 triple-negative breast cancer cells
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Concentration:4 μM
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Incubation Time:24 h
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Result:Did not induce significant degradation of PARP1 protein.
Chemical Information
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CAS No. 95-10-3
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Appearance Liquid (Density: 1.000±0.06 g/cm3)
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Molecular Weight 123.20
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Formula C8H13N
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Color Colorless to light yellow
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SMILES
NCC1C(C2)C=CC2C1
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Synonyms
JBP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 200 mg/mL (1623.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.1169 mL | 40.5844 mL | 81.1688 mL | 202.9221 mL |
| 5 mM | 1.6234 mL | 8.1169 mL | 16.2338 mL | 40.5844 mL | |
| 10 mM | 0.8117 mL | 4.0584 mL | 8.1169 mL | 20.2922 mL | |
| 15 mM | 0.5411 mL | 2.7056 mL | 5.4113 mL | 13.5281 mL | |
| 20 mM | 0.4058 mL | 2.0292 mL | 4.0584 mL | 10.1461 mL | |
| 25 mM | 0.3247 mL | 1.6234 mL | 3.2468 mL | 8.1169 mL | |
| 30 mM | 0.2706 mL | 1.3528 mL | 2.7056 mL | 6.7641 mL | |
| 40 mM | 0.2029 mL | 1.0146 mL | 2.0292 mL | 5.0731 mL | |
| 50 mM | 0.1623 mL | 0.8117 mL | 1.6234 mL | 4.0584 mL | |
| 60 mM | 0.1353 mL | 0.6764 mL | 1.3528 mL | 3.3820 mL | |
| 80 mM | 0.1015 mL | 0.5073 mL | 1.0146 mL | 2.5365 mL | |
| 100 mM | 0.0812 mL | 0.4058 mL | 0.8117 mL | 2.0292 mL |
5-Norbornene-2-methylamine Related Classifications
HY-W022007 Related Classifications
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