2. Others Metabolic Enzyme/Protease Stem Cell/Wnt Immunology/Inflammation Apoptosis Neuronal Signaling MAPK/ERK Pathway NF-κB Protein Tyrosine Kinase/RTK
  3. MEK Ferroptosis TNF Receptor NF-κB Reference Standards p38 MAPK Reactive Oxygen Species (ROS) VEGFR Amyloid-β NOD-like Receptor (NLR) Src Anaplastic lymphoma kinase (ALK) JNK ERK
  4. 5-O-Methylvisammioside (Standard)

5-O-Methylvisammioside (Standard)  (Synonyms: 4'-O-β-D-Glucosyl-5-O-methylvisamminol (Standard))

Cat. No.: HY-N0442R
Handling Instructions Technical Support

5-O-Methylvisammioside (4'-O-β-D-Glucosyl-5-O-methylvisamminol) (Standard) is the analytical standard of 5-O-Methylvisammioside. This product is intended for research and analytical applications. 5-O-Methylvisammioside is an orally active natural chromone glycoside and multiple biological activities. 5-O-Methylvisammioside inhibits ferroptosis by activating the Nrf2/HO-1 signaling axis. 5-O-Methylvisammioside alleviates intestinal barrier damage by inhibiting the ROS/NF-κB/NLRP3 pathway. 5-O-Methylvisammioside exerts a protective effect against acute liver injury by reducing ALT/AST, decreasing inflammatory infiltration, and inhibiting IκB-α phosphorylation and NF-κB nuclear translocation. 5-O-Methylvisammioside blocks the HMGB1/RAGE/MEK/ERK signaling axis to exert anti-tumor and anti-angiogenic effects. 5-O-Methylvisammioside improves depression-like behaviors by inhibiting Src kinase and the NF-κB pathway.

For research use only. We do not sell to patients.

5-O-Methylvisammioside (Standard)

5-O-Methylvisammioside (Standard) Chemical Structure

CAS No. : 84272-85-5

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Information

5-O-Methylvisammioside (4'-O-β-D-Glucosyl-5-O-methylvisamminol) (Standard) is the analytical standard of 5-O-Methylvisammioside. This product is intended for research and analytical applications. 5-O-Methylvisammioside is an orally active natural chromone glycoside and multiple biological activities. 5-O-Methylvisammioside inhibits ferroptosis by activating the Nrf2/HO-1 signaling axis. 5-O-Methylvisammioside alleviates intestinal barrier damage by inhibiting the ROS/NF-κB/NLRP3 pathway. 5-O-Methylvisammioside exerts a protective effect against acute liver injury by reducing ALT/AST, decreasing inflammatory infiltration, and inhibiting IκB-α phosphorylation and NF-κB nuclear translocation. 5-O-Methylvisammioside blocks the HMGB1/RAGE/MEK/ERK signaling axis to exert anti-tumor and anti-angiogenic effects. 5-O-Methylvisammioside improves depression-like behaviors by inhibiting Src kinase and the NF-κB pathway.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

452.45

Formula

C22H28O10
CAS No.
SMILES

O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC(C)([C@H]2OC3=C(C(OC)=C(C(C=C(C)O4)=O)C4=C3)C2)C)[C@@H]1O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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5-O-Methylvisammioside (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-O-Methylvisammioside (Standard)84272-85-54'-O-β-D-Glucosyl-5-O-methylvisamminol (Standard)MEKFerroptosisTNF ReceptorNF-κBReference Standardsp38 MAPKReactive Oxygen Species (ROS)VEGFRAmyloid-βNOD-like Receptor (NLR)SrcAnaplastic lymphoma kinase (ALK)JNKERKMitogen-activated protein kinase kinaseMAPKKMAP2KTumor Necrosis Factor ReceptorTNFRNuclear factor-κBNuclear factor-kappaBVascular endothelial growth factor receptorβ-amyloid peptideAβAbetaAnaplastic lymphoma kinaseALK tyrosine kinase receptorCD246Cluster of differentiation 246c-Jun N-terminal kinaseExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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