7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9)
7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9) is the 13C and 15N labeled 7-Methylxanthine. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi.
For research use only. We do not sell to patients.
- Formula: C213C4H6N15N2O2
- Molecular Weight:158.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 158.09
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Formula C213C4H6N15N2O2
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SMILES
O=[13C]1[15NH][13C]([13C]2=[13C]([15NH]1)[R]=CN2C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Caubet MS, et al. Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. J Pharm Biomed Anal. 2004 Feb 4;34(2):379-89. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
7-Methylxanthine-2,4,5,6-13C4, 1,3-15N2 (with variable 15N labeling at N9) Related Classifications
HY-W017163S Related Classifications
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