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Cat. No.: HY-122973

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7-Oxodehydroabietinol

7-Oxodehydroabietinol is a selective inhibitor targeting the human herpesvirus HHV-2. 7-Oxodehydroabietinol can be used in anti-herpesvirus drug development to target HHV-2 infection.

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CAS No.: 33980-71-1
Formule: C₂₀H₂₈O₂
Masse moléculaire:300.44

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

7-Oxodehydroabietinol Chemical Structure

CAS No.: 33980-71-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

7-Oxodehydroabietinol is a selective inhibitor targeting the human herpesvirus HHV-2. 7-Oxodehydroabietinol can be used in anti-herpesvirus drug development to target HHV-2 infection^[1]^[2].

IC₅₀ & Target

HHV-2

Voir tous les produits spécifiques à Isoform HSV :

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	30 μg/mL Compound: 12, 7-oxodehydroabietinol	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19892441]
Jurkat	IC₅₀	17 μg/mL Compound: 12, 7-oxodehydroabietinol	Cytotoxicity against human Jurkat cells after 48 hrs by MTT assay Cytotoxicity against human Jurkat cells after 48 hrs by MTT assay	[PMID: 19892441]
LoVo	IC₅₀	>25 μg/mL Compound: 33	Antiproliferative activity against human LoVo cells Antiproliferative activity against human LoVo cells	[PMID: 20022253]
QGY-7703	IC₅₀	>25 μg/mL Compound: 33	Antiproliferative activity against human QGY7703 cells Antiproliferative activity against human QGY7703 cells	[PMID: 20022253]
RAW264.7	IC₅₀	>100 μg/mL Compound: 33	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release	[PMID: 20022253]
Vero	IC₅₀	27 μg/mL Compound: 12, 7-oxodehydroabietinol	Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay	[PMID: 19892441]

In Vitro

7-Oxodehydroabietinol has a viral titer reduction factor (Rf) of 1×10¹ against HHV-2 at a concentration of 12.5 μg/mL and is inactive against HHV-1^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 33980-71-1
Masse moléculaire 300.44
Formule C₂₀H₂₈O₂
SMILES

O=C1C2=C(C=CC(C(C)C)=C2)[C@@]3(C)CCC[C@@](C)(CO)[C@]3([H])C1
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Seca AM, et al. Diterpene constituents of leaves from Juniperus brevifolia. Phytochemistry. 2008 Jan;69(2):498-505. [Content Brief]

[2]. Agudelo Gómez, et al. "Anti HHV-1 and HHV-2 activity in vitro of abietic and dehydroabietic acid derivatives." (2012).

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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7-Oxodehydroabietinol

Voir tous les produits spécifiques à Isoform HSV

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

7-Oxodehydroabietinol Related Classifications

HY-122973 Related Classifications