1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR
  3. Nazartinib S-enantiomer

Nazartinib S-enantiomer  (Synonyms: EGF816 (S-enantiomer))

Cat. No.: HY-12872B Purity: 98.66%
COA Handling Instructions

Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.

For research use only. We do not sell to patients.

Nazartinib S-enantiomer Chemical Structure

Nazartinib S-enantiomer Chemical Structure

CAS No. : 1508256-20-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 1307 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 1307 In-stock
Estimated Time of Arrival: December 31
Solid
2 mg USD 600 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Nazartinib S-enantiomer:

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Description

Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.

Molecular Weight

495.02

Formula

C26H31ClN6O2

CAS No.
SMILES

O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[[email protected]@H]4CN(C(/C=C/CN(C)C)=O)CCCC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (101.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0201 mL 10.1006 mL 20.2012 mL
5 mM 0.4040 mL 2.0201 mL 4.0402 mL
10 mM 0.2020 mL 1.0101 mL 2.0201 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.75 mg/mL (5.56 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.75 mg/mL (5.56 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Nazartinib S-enantiomer
Cat. No.:
HY-12872B
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