1. Epigenetics
    PROTAC
  2. Epigenetic Reader Domain
    PROTAC

MZ 1 

Cat. No.: HY-107425 Purity: 98.51%
Handling Instructions

MZ 1 is a BRD4 protein degrader based on PROTAC technology.

For research use only. We do not sell to patients.

MZ 1 Chemical Structure

MZ 1 Chemical Structure

CAS No. : 1797406-69-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 607 In-stock
Estimated Time of Arrival: December 31
1 mg USD 90 In-stock
Estimated Time of Arrival: December 31
5 mg USD 310 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

MZ 1 is a BRD4 protein degrader based on PROTAC technology.

IC50 & Target

BRD4[1]

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (24.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9974 mL 4.9868 mL 9.9737 mL
5 mM 0.1995 mL 0.9974 mL 1.9947 mL
10 mM 0.0997 mL 0.4987 mL 0.9974 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3.58 mg/mL (3.57 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.58 mg/mL (3.57 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3.58 mg/mL (3.57 mM); Clear solution

References
Molecular Weight

1002.64

Formula

C₄₉H₆₀ClN₉O₈S₂

CAS No.

1797406-69-9

SMILES

CC1=C(C)SC2=C1C(C3=CC=C(Cl)C=C3)=N[[email protected]@H](CC(NCCOCCOCCOCC(N[[email protected]@H](C(C)(C)C)C(N4[[email protected]@H](C[[email protected]@H](O)C4)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 98.51%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
MZ 1
Cat. No.:
HY-107425
Quantity:

MZ 1

Cat. No.: HY-107425