Others

2-Hydroxymethyl olanzapine is a metabolite and a degradation product of Olanzapine (HY-14541)^[1][2].

Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding.

(R)-ML375 ((R)-VU0483253) is an enantiomer of ML375 (HY-12567). (R)-ML375 is devoid of M₅ mAChR activity (hM₅, IC₅₀>30 μM).

15-deoxy-Δ12,14-Prostaglandin J2 glutathione (15-deoxy-Δ12,14-PGJ2 glutathione) is a non-enzymatic adduct formed from 15-deoxy-Δ12,14-PGJ2 and glutathione. The biological properties of this compound have not been characterized.

Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λ_ex = 430 nm, λ_em = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes.

Bimatoprost acid-d₄ (17-Phenyl trinor PGF2α-d₄) is the deuterium labeled Bimatoprost acid.

Solvent violet 9 is a dye for recognizing DNA.

A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (K_i=4.3 µM), casein kinase II (K_i=5.1 µM) and myosin light chain kinase (MLCK) (K_i=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with K_i values of 47 µM and 80 µM, respectively.

TSPC is a phytohormone gibberellin (GA) perception inhibitor with an IC₅₀ value of 10 μM in vitro.

1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H₂O₂, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions.

N-Butyl cinnamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of Methionine (HY-13694).

Chlorthiamid is a broad-spectrum herbicide. Chlorthiamid is an olfactory toxicant with a high in vivo covalent binding in the olfactory mucosa of mice.

GJ072 is a read-through compound (RTCs). GJ072 can induce “readthrough”.

Isorutarin is a natural product that can be isolated from the seeds of Apium graueolens.

PAT-347 is an inhibitor of autotaxin (ATX, ENPP-2). PAT-347 binds only to the hydrophobic channel of ATX, without occupying its hydrophobic pocket and catalytic site. PAT-347 blocks the binding of lysophosphatidylcholine (LPC) to the catalytic site of ATX.

Glycerophosphoric acid (disodium salt hydrate) (α and β mixture) is a complex contains α and β Glycerophosphoric acid isomers.

ML266 is glucocerebrosidase (GCase) molecule chaperone with IC₅₀ of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease.

Myristoyl glutamic acid sodium is a common ingredient in cosmetics/creams. Myristoyl glutamic acid sodium, a surfactant belonging to the amino acid, has mild cleaning properties and is also foamy and mildly bacteriostatic.

5-Hydroxyomeprazole sodium is the major metabolite of Omeprazole (HY-B0113). Measuring 5-Hydroxyomeprazole levels in plasma can determine the extent of Omeprazole metabolism.