Others

HEP-50768 is an orally active and selective MRGPRX4 (hX4) antagonist. HEP-50768 suppresses basal and bile-acid-stimulated hX4 activity. HEP-50768 binds the receptor’s transmembrane pocket and induces extracellular loop rearrangements. HEP-50768 modulates GPCR microswitch motifs and reduces bile-acid-induced pruritic scratching behaviors. HEP-50768 can be used for the research of cholestatic pruritus.

GR119566X is a 5-HT₃ receptor ligand with a pK_i value of 8.80 against prufied 5-HT₃ receptor. GR119566X can be used for 5-HT₃ receptor purification.

DCAF1 ligand 2 (Tert-butyl (2-((2-(1-(4-chlorophenyl)cyclohexyl)-7-(piperazin-1-yl)quinazolin-4-yl)amino)ethyl)carbamate) is a ligand of the E3 connecting enzyme DCAF1. DCAF1 ligand 2 can be used for the synthesis of PROTACs.

DSPE-PEG8-OH is a monodisperse lipid-polyethylene glycol conjugate featuring a hydrophobic 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) anchor, an 8-unit discrete (PEG₈) spacer, and a terminal hydroxyl (-OH) group. DSPE-PEG8-OH is primarily used in liposome formulation, nanoparticle surface modification, and targeted drug delivery systems.

Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % is a non-toxic polymer with good hydrophilicity and biocompatibility. Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % has high tensile strength and excellent film-forming property. Poly(vinyl alcohol-co-ethylene) ethylene 32 mol % can be used in research related to packaging materials.

Chitinase-IN-2 is an insecticide that can inhibit the activity of chitinase and N-acetylhexosaminidase, with inhibition percentages of 98% and 92% at concentrations of 50 μM and 20 μM, respectively.

IDH1 ligand 1 (Compound 18) can serve as a negative control for the IDH1 target, with no detectable affinity for wild-type IDH1 and an IC₅₀ >10,000 nM.

LY-22CD is a Drug-Linker Conjugates for ADC. LY-22CD consists of an ADC payload and a linker, and can be used for ADC synthesis.

trans-Zeatin (Standard) is the analytical standard of trans-Zeatin. This product is intended for research and analytical applications. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.

α-Cyclobutylglycine is a Glycine (HY-Y0966) derivative.

2-(Tetrahydropyran-4-yl)glycine is a Glycine (HY-Y0966) derivative.

(R)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid is a Glycine (HY-Y0966) derivative.

(R)-2-amino-3-cyclobutylpropanoic acid is an alanine derivative.

Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota.

1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol)-d₅₄ (sodium) is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium).

1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a ribofuranose nucleoside analogue.

N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonine is a threonine derivative.

TNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC₅₀s of 259 nM and 1100 nM.

Poly(4-vinylphenol) is a polymer cross-linking agent that can be used to prepare non-toxic films. Poly(4-vinylphenol) is a sensitizer of titania for visible light photocatalysis. Poly(4-vinylphenol) also can be used as a water resistive wood adhesive, as a gate dielectric insulator in organic field effect transistors, and as a responsive surface coating.

NH-bis (C1-Boc) is an amino compound that can be used as an intermediate in organic synthesis-related research. NH-bis (C1-Boc) can also serve as a linker for antibody-drug conjugate (ADC) synthesis-related research.