GR119566X
GR119566X is a 5-HT3 receptor ligand with a pKi value of 8.80 against prufied 5-HT3 receptor. GR119566X can be used for 5-HT3 receptor purification.
For research use only. We do not sell to patients.
- CAS No.: 237752-42-0
- Formula: C20H24N4O
- Molecular Weight:336.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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5-HT3 Receptor |
GR119566X (12.5 mg; 16 h) is successfully coupled to Affi-Gel 15 to form an affinity resin that specifically retains solubilized 5-HT3 receptors from porcine cerebral cortex, enabling receptor purification[1].
GR119566X (60 min at 37°C) binds to membrane-bound, solubilized, and affinity-purified 5-HT3 receptors from porcine cerebral cortex with consistent high affinity, as shown by pKi values ranging from 8.21 to 8.80[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 237752-42-0
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Molecular Weight 336.43
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Formula C20H24N4O
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SMILES
NCCCN1C(CCC(C2=O)CC3=C(N=CN3)C)=C2C4=C1C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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