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Bacterial Related Products (8745)
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Antibodies (14)
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Related Compound Screening Libraries (1)
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NDM-622
0 ImagesCat. No.: HY-184325NDM-622 is a Colistin (HY-113678) adjuvant. NDM-622 weakly inhibits IKKβ with an IC50 of 20.40 μM. NDM-622 reduces the minimum inhibitory concentration of colistin against colistin-highly-resistant Acinetobacter baumannii and Klebsiella pneumoniae. NDM-622 decreases bacterial colony-forming units in a mouse peritonitis model infected with colistin-highly-resistant Klebsiella pneumoniae. NDM-622 does not modify bacterial lipid A, induce reactive oxygen species production, or increase bacterial membrane permeability. NDM-622 can be used in the research of extensively drug-resistant Gram-negative bacterial infections, colistin-resistant Acinetobacter baumannii infections, and Klebsiella pneumoniae infections. -
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Meridinol
0 ImagesCat. No.: HY-N3296CAS No.: 120051-54-9Synonyms: (-)-MeridinolMeridinol ((-)-Meridinol) shows antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi. -
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Sulisatin
0 ImagesCat. No.: HY-122307CAS No.: 54935-03-4Synonyms: DAN-603Sulisatin (DAN-603) is an anionic laxative that is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon during oral administration. -
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FuK
0 ImagesCat. No.: HY-P11615FuK is a WK2-analog antimicrobial peptide modified with fluorinated unnatural amino acids. FuK has an LD50 of 72.34 mg/kg in mice, shows no hemolytic activity, with high stability against trypsin, chymotrypsin, and saline environments. FuK exerts bactericidal effects by enhancing the permeability of bacterial outer membranes, inducing depolarization of cytoplasmic membranes, and disrupting membrane potential balance against bacterias such as Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and MRSA. FuK exhibits synergistic antimicrobial activity with polymyxin B (HY-149179), vancomycin (HY-B0671), and ciprofloxacin (HY-B0356), and also inhibits Ciprofloxacin-induced bacterial drug resistance. FuK has in vivo safety, effectively reduces bacterial load and inflammatory cell infiltration in a mouse MRSA model, and promotes collagen fiber formation in skin wounds. -
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- PP113
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- Purpurin (Standard)
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Nifursol (Standard)
0 ImagesNifursol (Standard) is the analytical standard of Nifursol (HY-B1703). This product is used for research and analytical applications. Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals. -
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FtsZ-IN-8
0 ImagesCat. No.: HY-149226FtsZ-IN-8 is a potent FtsZ inhibitor, to promote FtsZ polymerization and inhibit GTPase activity of FtsZ. Thus, FtsZ-IN-8 inhibits bacterial division to lead to death of bacterial cells. FtsZ-IN-8 shows bactericidal activity with no significant tendency to trigger bacterial resistance as well as rapid bactericidal properties. And FtsZ-IN-8 shows low hemolytic activity and cytotoxicity to mammalian cells. -
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MtTMPK-IN-4
0 ImagesCat. No.: HY-143452CAS No.: 2225889-49-4MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase inhibitor. MtTMPK-IN-4 is a potent antibacterial agent. -
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Droxacin
0 ImagesCat. No.: HY-184088CAS No.: 35067-47-1Droxacin is an antibacterial agent structurally related to furo[2,3-g]quinoline derivatives, with in vitro activity against Gram-positive and Gram-negative bacteria. Droxacin can be used in the research of bacterial infections. -
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Anti-MRSA agent 23
0 ImagesCat. No.: HY-168873CAS No.: 2607085-75-4Anti-MRSA agent 23 (compound 11) is a potent anti-methicillin-resistant Staphylococcus aureus agent. Anti-MRSA agent 23 shows antibacterial and antibiofilm activities. Anti-MRSA agent 23 accelerates the reconstruction and healing of MRSA-infected cutaneous wounds by decreasing bacterial loads, attenuating inflammation, and promoting angiogenesis. -
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DprE1-IN-9
0 ImagesCat. No.: HY-149581CAS No.: 2906099-98-5DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates. -
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Calpinactam
0 ImagesCat. No.: HY-120733CAS No.: 1205538-83-5Synonyms: FKI-4905Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively. -
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WLBU2
0 ImagesCat. No.: HY-P11085CAS No.: 847061-43-2WLBU2 is a engineered cationic antimicrobial peptide (eCAP) that overcomes the environmental sensitivity of natural antimicrobial peptides (AMPs). WLBU2 exhibits rapid bactericidal effect, with the MIC values of ≤ 10 μM against both Gram-negative and Gram-positive bacteria including MRSA, vancomycin-resistant enterococci, K. pneumoniae, E.aerogenes, E. cloacae, Escherichia coli, et, al. WLBU2 prevents P. aeruginosa biofilm growth and retains its activity in an environment rich in mucus, low pH and high salt concentrations without negative effects on human airway epithelial cells. WLBU2 can be used for the studies of cystic fibrosis (CF) and Pseudomonas aeruginosa infections. -
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Sulfaethoxypyridazine
0 ImagesSulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs. -
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MurA-IN-5
0 ImagesCat. No.: HY-172132MurA-IN-5 (compound 4c) exhibits (MIC) = 1.95 μg/mL against Escherichia coli and demonstrating significant potency as a MurA inhibitor with (IC50) of 3.77 μg/mL. MurA-IN-5 displays an antibiofilm activity against multiple microorganisms, indicating its potential to combat biofilm-related infections. -
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MtTMPK-IN-2
0 ImagesCat. No.: HY-144664CAS No.: 2799607-71-7MtTMPK-IN-2 (compound 15) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 1.1 μM. MtTMPK-IN-2 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-2 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC50 = 6.1 μM). MtTMPK-IN-2 can be used for researching tuberculosis. -
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Vasicine hydrochloride (Standard)
0 ImagesCat. No.: HY-N1103ARCAS No.: 7174-27-8Synonyms: Peganine hydrochloride (Standard)Vasicine (hydrochloride) (Standard) is the analytical standard of Vasicine (hydrochloride). This product is intended for research and analytical applications. Vasicine hydrochloride (peganine hydrochloride) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine hydrochloride activates PI3K/Akt signaling pathway, exhibits antioxidant, anti-inflammatory and antibacterial activities. -
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Antibacterial agent 12
0 ImagesCat. No.: HY-126629CAS No.: 2382921-99-3Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria. -
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Sulfaguanidine-d4
0 ImagesCat. No.: HY-B1267SPurity: 98.0%Sulfaguanidine-d4 is the deuterium labeled Sulfaguanidine. Sulfaguanidine, belongs to the class of sulfonamide agent, is an orally active antibiotic. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery. -
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