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Cat. No.: HY-184088

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Droxacin

Droxacin is an antibacterial agent structurally related to furo[2,3-g]quinoline derivatives, with in vitro activity against Gram-positive and Gram-negative bacteria. Droxacin can be used in the research of bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 35067-47-1
Formula: C₁₄H₁₃NO₄
Molecular Weight:259.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Droxacin Chemical Structure

CAS No.: 35067-47-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Bacterial Infection

Droxacin exhibits broad-spectrum in vitro antibacterial activity, with an MIC ≤ 0.78 μg/mL against most Gram-negative bacteria such as Escherichia coli and Proteus spp.; it shows relatively weak inhibitory activity against Pseudomonas aeruginosa and Streptococcus pyogenes, with MIC values of 25 μg/mL and 100 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Droxacin shows an intravenous acute toxicity LD₅₀ of 170 mg/kg in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 35067-47-1
Molecular Weight 259.26
Formula C₁₄H₁₃NO₄
SMILES

O=C(C1=CN(CC)C2=CC3=C(C=C2C1=O)OCC3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tanaka Y, et al. Synthesis of Antimicrobial Agents. VII. Synthesis and Antibacterial Activities of Furo[2,3-g]quinoline Derivatives. Chemical & Pharmaceutical Bulletin, 1984, 32(12): 4923-4928. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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