1205538-83-5
Chemical Structure
Calpinactam
Synonym(s): FKI-4905
- CAS No.: 1205538-83-5
- Formula:C38H57N9O8
- Molecular Weight:767.91
IUPAC Name: (R)-4-((S)-2-((S)-2-((R)-2-amino-3-phenylpropanamido)-4-methylpentanamido)-3-(1H-imidazol-4-yl)propanamido)-5-(((2R,3S)-3-methyl-1-oxo-1-(((S)-2-oxoazepan-3-yl)amino)pentan-2-yl)amino)-5-oxopentanoic acid
InChIKey: GPDRWULXOJRYOR-XHGFRBTRSA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC=N1)C(N[C@H](CCC(O)=O)C(N[C@H]([C@@H](C)CC)C(N[C@@H]2C(NCCCC2)=O)=O)=O)=O)=O)[C@@H](CC3=CC=CC=C3)N
Biological Activity: Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively[1].
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Calpinactam | Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively. | |||||||||||||||||||||
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