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CDK Related Products (487)
Related Products (487)
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CDK4/6-IN-24
0 ImagesCat. No.: HY-172146CAS No.: 2662813-96-7CDK4/6-IN-24 (Compound A) is the inhibitor for CDK4/6. CDK4/6-IN-24 exhibits board-spectrum antitumor activity that inhibits multi cancer cells with IC50 of submicromolar levels.
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Anticancer agent 238
0 ImagesCat. No.: HY-162670Anticancer agent 238 (compound 5) is an anticancer agent with a notably strong binding affinity towards the CDK-5 enzyme. Anticancer agent 238 shows a strong efficacy agains HCT116 and MCF7 cells, with IC50 values of 13.46 µM and 16.43 µM, respectively.
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PROTAC FLT3/CDK9 degrader-1
0 ImagesCat. No.: HY-148521CAS No.: 3033084-05-5
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SKLB70326
0 ImagesCat. No.: HY-116204CAS No.: 1257317-77-3SKLB70326 is a small molecule inhibitor of cell cycle progression that induces cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. SKLB70326 is involved in downregulating cyclin-dependent kinase (CDK) 2, CDK4, and CDK6, while also activating PARP, caspase-3, caspase-9, and Bax, and downregulating Bcl-2.
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CLK3 Recombinant Human Active Protein Kinase
0 ImagesCat. No.: HY-E70692CLK3 is a nuclear dual-specificity kinase has been shown to undergo conserved alternative splicing to generate catalytically active (Clk) and inactive (ClkT) isoforms. CLK3 Recombinant Human Active Protein Kinase is a recombinant CLK3 protein that can be used to study CLK3-related functions.
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CDK2-IN-24
0 ImagesCat. No.: HY-162270CDK2-IN-24 (compound 3f) is an inhibitor of cyclin-dependent kinase 2 with an elevated binding energy value .
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[pThr3]-CDK5 Substrate
![[pThr3]-CDK5 Substrate](https://file.medchemexpress.com/product_pic/hy-p1906.gif "Click to View [pThr3]-CDK5 Substrate Product Detail")
0 ImagesCat. No.: HY-P1906CAS No.: 1670273-47-8
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CDK7-IN-22
0 ImagesCat. No.: HY-153950CAS No.: 2173190-60-6
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LBM22
0 ImagesCat. No.: HY-168209LBM22 is a CDC2-like kinase 2 (CLK2) inhibitor with the IC50 of 3.9 nM. LBM22 has antiproliferative activity and inhibits serine/arginine-rich (SR) protein phosphorylation. LBM22 down-regulates the expression of Wnt-related proteins and anti-apoptotic proteins and can be used for study of non-small cell lung cancer.
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CDK7-IN-14
0 ImagesCat. No.: HY-147598CAS No.: 2765676-49-9
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CDKI-IN-1
0 ImagesCat. No.: HY-169557CAS No.: 1185726-51-5CDKI-IN-1 (Compound SNX12) is a cyclin-dependent kinase inhibitor (CDKI) inhibitor that can be used for research into degenerative diseases of the central nervous system.
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Crozbaciclib fumarate
0 ImagesCrozbaciclib fumarate is a CDK4/6 inhibitor with IC50s of 3 and 1 nM, respectively.
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Otviciclib
0 ImagesCat. No.: HY-177501CAS No.: 2228039-87-8Otviciclib (Compound 86) is a CDK inhibitor. Otviciclib has potent anti-proliferative activity against solid tumor cells (such as HCT116, NCIH82 and DU145 cells) with no significant toxicity to normal cells, and effectively induces the G2/M phase cells arrest and apoptosis. Otviciclib has a broad-spectrum anticancer activity, such as colon, pancreatic and lung cancer.
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Dehydrodiisoeugenol-d4
0 ImagesCat. No.: HY-N0589SDehydrodiisoeugenol-d4 is the deuterium labeled Dehydrodiisoeugenol (HY-N0589). Dehydrodiisoeugenol is an orally active anti-inflammatory and anti-tumor agent. Dehydrodiisoeugenol inhibits the proliferation of colorectal cancer cells, and induces apoptosis, autophagy, endoplasmic reticulum stress and cell cycle arrest. Dehydrodiisoeugenol also exerts anti-inflammatory effects by inhibiting the activation of NF-κB and the expression of COX-2. Dehydrodiisoeugenol can be used in the research related to colorectal cancer, inflammatory diseases and ulcerative colitis.
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Lenoremycin
0 ImagesCat. No.: HY-129694CAS No.: 51257-84-2Synonyms: Ro 21-6150; Antibiotic A-130-ALenoremycin (Ro 21-6150) is a microbial metabolite. Lenoremycin decreases β-catenin and cyclin D1 proteins levels. Lenoremycin decreases cancer stem cells (CSCs) populations via inducing reactive oxygen species production.
