Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2499)
Related Products (2499)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Antileishmanial agent-10
0 ImagesCat. No.: HY-147766CAS No.: 2397639-33-5Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
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HAT-IN-8
0 ImagesCat. No.: HY-155024CAS No.: 3036127-14-4HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM). HAT-IN-8 can be used for the research of Human African trypanosomiasis.
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Temporin-SHa
0 ImagesCat. No.: HY-P11102CAS No.: 1065010-73-2Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC50 = 5-20 μM), and Trypanosoma cruzi (IC50 = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.).
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Malonganenone A
0 ImagesCat. No.: HY-126601CAS No.: 882403-69-2
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Antileishmanial agent-4
0 ImagesCat. No.: HY-146744CAS No.: 2922333-23-9Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent.
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Norketotifen
0 ImagesCat. No.: HY-W665882CAS No.: 34580-20-6Norketotifen is the active metabolite of Ketotifen (HY-B0157). Norketotifen exhibits skin anti-inflammatory activity, anti-malarial activity, and antipruritic activity against non-histamine-mediated dog itching in mice. Norketotifen effectively inhibits TNF-α release without causing any sedative side effects. Norketotifen can be used for research on non-sedating anti-inflammatory agents.
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2-Thiophenecarboxaldehyde (Standard)
0 ImagesSynonyms: Thiophene-2-carboxaldehyde (Standard)2-Thiophenecarboxaldehyde (Standard) is the analytical standard of 2-Thiophenecarboxaldehyde. This product is intended for research and analytical applications. 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities.
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Tirandamycin A
0 ImagesCat. No.: HY-126406CAS No.: 34429-70-4Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.
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Selamectin (Standard)
0 ImagesSelamectin (Standard) is the analytical standard of Selamectin. This product is intended for research and analytical applications. Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM.
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Tetramisole
0 ImagesTetramisole is an orally active, selective inward rectifier potassium channel agonist with an EC50 of approximately 30 μM for the Kir2.1 subunit. Tetramisole is also an anti-nematode agent that blocks neuromuscular transmission by non-competitive depolarization. Tetramisole promotes the forward transport of Kir2.1 channels, hyperpolarizes the resting potential (RP), shortens the action potential duration (APD), inhibits intracellular calcium overload and the PKA signaling pathway, and exerts anti-arrhythmic and anti-myocardial remodeling activities. Tetramisole can be used in cardiac electrophysiology research and research related to myocardial ischemia and heart failure.
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Antiproliferative agent-56
0 ImagesCat. No.: HY-169099Antiproliferative agent-56 (Compound 31) is an antimalarial agent, that inhibits Plasmodium falciparum 3D7 (Pf3D7) with an IC50 >12.5 (48h) and 0.03 μM (98h), and reveals a slow-acting property.
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Mebendazole-d8
0 ImagesCat. No.: HY-17595S1CAS No.: 1286787-80-1Mebendazole-d8 is the deuterium labeled Mebendazole. Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations; has been found as a hedgehog inhibitor.
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Antitrypanosomal agent 19
0 ImagesCat. No.: HY-163003Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice.
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Lucanthone hydrochloride
0 ImagesLucanthone hydrochloride is an endonuclease inhibitor of Apurinic endonuclease-1 (APE-1).
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Antimalarial agent 64
0 ImagesCat. No.: HY-184182CAS No.: 2770244-63-6Antimalarial agent 64 is an orally active acridine-based antimalarial derivative and also a rapid-acting inhibitor of hemozoin formation. Antimalarial agent 64 exhibits nanomolar inhibitory activity against field isolates of Plasmodium falciparum and Plasmodium vivax. Antimalarial agent 64 localizes near the digestive vacuole of Plasmodium. Antimalarial agent 64 can be used for the research of malaria.
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NCR247
0 ImagesCat. No.: HY-P11767CAS No.: 1372669-36-7NCR247 is a defensin-like nodule cysteine-rich (NCR) peptide and heme chelator. NCR247 induces iron starvation responses in Sinorhizobium meliloti and Medicago truncatula, and supports nitrogenase activity. NCR247 can be used in research related to periodontal disease and toxoplasmosis.
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(2R,4R)-UCB7362 hydrochloride
0 ImagesCat. No.: HY-156063ACAS No.: 2610631-18-8
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2,3-Diphosphoglyceric acid-d3 ammonium
0 ImagesCat. No.: HY-113050SACAS No.: 2712139-19-8Synonyms: 2,3-DPG-d3 ammonium2,3-Diphosphoglyceric acid-d3 ammonium (2,3-DPG-d3 ammonium) is the deuterium labeled 2,3-Diphosphoglyceric acid (HY-113050). 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD).
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Nitenpyram-d3-1
0 ImagesCat. No.: HY-B0820S1Nitenpyram-d3-1 is the deuterium labeled Nitenpyram (HY-B0820). Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.
