Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Alle Parasite Isoform-spezifische Produkte anzeigen
All Product Categories
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Parasite Verwandte Produkte (2480)
Verwandte Produkte (2480)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Pirimicarb (Standard)
0 ImagesPirimicarb (Standard) is the analytical standard of Pirimicarb. This product is intended for research and analytical applications. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide.
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LXE408 fumarate
0 ImagesArt. -Nr.: HY-131350ACAS. Nr.: 3026790-19-9LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 μM for L. donovani proteasome and an EC50 of 0.04 μM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
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CGP-20376
0 ImagesArt. -Nr.: HY-19054CAS. Nr.: 81059-04-3CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity.
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Andrographolide-d
0 ImagesArt. -Nr.: HY-N0191SSynonyms: Andrographis-dAndrographolide-d (Andrographis-d) is the deuterium labeled Andrographolide (HY-N0191). Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.
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Etofamide
0 ImagesArt. -Nr.: HY-123652CAS. Nr.: 25287-60-9Etofamide is an antimicrobial agent with IC50 value of 5.96 mg/L against amoeba.
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Pefloxacin-d3
0 ImagesSynonyms: Pefloxacinium-d3Pefloxacin-d3 (Pefloxacinium-d3) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
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Antiparasitic agent-2
0 ImagesArt. -Nr.: HY-146041CAS. Nr.: 2494277-80-2Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM).
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Albendazole sulfoxide-d7
0 ImagesArt. -Nr.: HY-12785S1CAS. Nr.: 2469575-37-7Synonyms: Ricobendazole-d7; Albendazole oxide-d7Albendazole sulfoxide-d7 is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
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Clindamycin phosphate hydrochloride
0 ImagesArt. -Nr.: HY-B1064ACAS. Nr.: 64023-51-4Synonyms: Clindamycin 2-phosphate hydrochloride; U-28508 hydrochlorideClindamycin phosphate (Clindamycin 2-phosphate) hydrochloride is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate hydrochloride is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate hydrochloride can be used for researching acne and bacterial vaginosis.
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Koshidacin B
0 ImagesArt. -Nr.: HY-N10624CAS. Nr.: 2925302-01-6Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against P. falciparum FCR3 and K1 strain with IC50 values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection.
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Antileishmanial agent-10
0 ImagesArt. -Nr.: HY-147766CAS. Nr.: 2397639-33-5Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
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HAT-IN-8
0 ImagesArt. -Nr.: HY-155024CAS. Nr.: 3036127-14-4HAT-IN-8 (Compound 38) is a BBB-penetrable T. brucei inhibitor (EC50: 0.18 μM). HAT-IN-8 can be used for the research of Human African trypanosomiasis.
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Temporin-SHa
0 ImagesArt. -Nr.: HY-P11102CAS. Nr.: 1065010-73-2Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC50 = 5-20 μM), and Trypanosoma cruzi (IC50 = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.).
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Malonganenone A
0 ImagesArt. -Nr.: HY-126601CAS. Nr.: 882403-69-2
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Antileishmanial agent-4
0 ImagesArt. -Nr.: HY-146744CAS. Nr.: 2922333-23-9Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent.
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Norketotifen
0 ImagesArt. -Nr.: HY-W665882CAS. Nr.: 34580-20-6Norketotifen is the active metabolite of Ketotifen (HY-B0157). Norketotifen exhibits skin anti-inflammatory activity, anti-malarial activity, and antipruritic activity against non-histamine-mediated dog itching in mice. Norketotifen effectively inhibits TNF-α release without causing any sedative side effects. Norketotifen can be used for research on non-sedating anti-inflammatory agents.
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2-Thiophenecarboxaldehyde (Standard)
0 ImagesSynonyms: Thiophene-2-carboxaldehyde (Standard)2-Thiophenecarboxaldehyde (Standard) is the analytical standard of 2-Thiophenecarboxaldehyde. This product is intended for research and analytical applications. 2-Thiophenecarboxaldehyde (Thiophene-2-carboxaldehyde) is an antibiotic that exhibits antibacterial and nematicidal activities.
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Tirandamycin A
0 ImagesArt. -Nr.: HY-126406CAS. Nr.: 34429-70-4Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.
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Selamectin (Standard)
0 ImagesSelamectin (Standard) is the analytical standard of Selamectin. This product is intended for research and analytical applications. Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm, Lymphatic filariae, and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC50 of 120 nM.
