81059-04-3
Chemical Structure
CGP-20376
- CAS No.: 81059-04-3
- Formula:C16H20N2O3S3
- Molecular Weight:384.54
IUPAC Name: 3-(((2-(tert-butyl)-5-methoxybenzo[d]thiazol-6-yl)carbamothioyl)thio)propanoic acid
InChIKey: SGSGNVTYYAWSKN-UHFFFAOYSA-N
SMILES: O=C(O)CCSC(NC1=C(OC)C=C2N=C(C(C)(C)C)SC2=C1)=S
Biological Activity: CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity[1][2].
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CGP-20376 | CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity. | |||||||||||||||||||||
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- [1]. J W Mak, et al. Antifilarial activity of CGP 20376 against subperiodic Brugia malayi in the leaf-monkey Presbytis cristata. Trop Med Parasitol. 1990 Mar;41(1):10-2. [Content Brief]
- [2]. P Weber. Effects of the two new anthelmintic agents CGP 6140 and CGP 20376 on adult Paragonimus uterobilateralis in the experimental host Sigmodon hispidus. Trop Med Parasitol. 1987 Dec;38(4):335-6. [Content Brief]
Keywords