2494277-80-2
2494277-80-2
Chemical Structure
Antiparasitic agent-2
- CAS No.: 2494277-80-2
- Formula:C20H17N3O3
- Molecular Weight:347.37
IUPAC Name: 1-ethyl-3-hydroxy-3-(1-(3-phenyl-1,2,4-oxadiazol-5-yl)vinyl)indolin-2-one
InChIKey: FKBCCMOTQVAZNH-UHFFFAOYSA-N
SMILES: O=C1N(CC)C2=C(C=CC=C2)C1(O)C(C3=NC(C4=CC=CC=C4)=NO3)=C
Biological Activity: Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM)[1].
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Antiparasitic agent-2 | Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC50 = 26.79 μM). | |||||||||||||||||||||
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References
Keywords
